2007
DOI: 10.1590/s1517-83822007000100030
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Evaluation of the antimicrobial activity of crude extracts and isolated constituents from Chresta scapigera

Abstract: Crude extracts and eight isolated compounds from Chresta scapigera were evaluated for antibacterial and antifungal activities by the agar-well diffusion method. Twenty strains, including Gram-positive and Gramnegative bacteria and yeasts were used in the bioassay. Hexane extracts presented the best results while ethanol extracts did not indicate inhibition of the microbial growth. Amongst the evaluated compounds β-amyrin acetate, tiliroside and luteolin showed the strongest antimicrobial effect.

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Cited by 49 publications
(26 citation statements)
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“…Antimicrobial activity of extracts was determined by the agar well diffusion method (23). Bacteria used as indicator organism were cultivated on nutrient agar medium at 36 ± 1ºC for 24 hour while the yeast were cultivated on Yeast malt extract agar at 26 ± 1ºC for 48 to 72 hour.…”
Section: Antimicrobial Activitymentioning
confidence: 99%
“…Antimicrobial activity of extracts was determined by the agar well diffusion method (23). Bacteria used as indicator organism were cultivated on nutrient agar medium at 36 ± 1ºC for 24 hour while the yeast were cultivated on Yeast malt extract agar at 26 ± 1ºC for 48 to 72 hour.…”
Section: Antimicrobial Activitymentioning
confidence: 99%
“…In addition, high cost and adverse side effects are commonly associated with popular synthetic antibiotics (such as hypersensitivity, allergic reactions, immjunosupression etc.) and are major burning global issues in treating infectious diseases [4]. Although pharmacological industries had produced considerable number of commercial antibiotics time to time but resistance in pathogens towards these drugs too has increased at high rate and mult-drug resistant microorganisms have exacerbated the situation [5].…”
Section: Introductionmentioning
confidence: 99%
“…The bioactive compounds were mainly flavonoids (luteolin, kaempferol and apigenin) and triterpenoids (Schinor et al, 2007).…”
Section: Resultsmentioning
confidence: 99%