2007
Evaluation of the antimicrobial activity of crude extracts and isolated constituents from Chresta scapigera
Abstract: Crude extracts and eight isolated compounds from Chresta scapigera were evaluated for antibacterial and antifungal activities by the agar-well diffusion method. Twenty strains, including Gram-positive and Gramnegative bacteria and yeasts were used in the bioassay. Hexane extracts presented the best results while ethanol extracts did not indicate inhibition of the microbial growth. Amongst the evaluated compounds β-amyrin acetate, tiliroside and luteolin showed the strongest antimicrobial effect.
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Cited by 65 publications
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“…It was also observed that the tested extract was inactive against E.coli, whereas the isolated compound exhibited a antimicrobial effect. However, in several previous experiments (Schinor et al 2007;Dos Santos et al 2012) also it has been found that the extracts do not inhibit the grow of microorganisms, but their isolated compounds demonstrate an antimicrobial effect. This is because components are present in the extract act antagonistically and thus reduce the activity of the extract.…”
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confidence: 90%