Summary

Pesticide Product Use and Risk of Non-Hodgkin Lymphoma in Women

“…For instance, occupational exposure to pesticides is often accompanied by exposure to other possible hazardous substances, such as solvents, fuels, and dusts (Maroni and Fait 1993; Morrison et al 1992), that have been associated with increased NHL risk (Mao et al 2000; Rego 1998). Similarly, people who use pesticides in and around the home may tend to use other household chemicals more often than those who do not.…”

“…Furthermore, it has been reported that exposure to certain pesticides synergistically increases the mutagenicity of diet-derived heterocyclic amines (Wagner et al 2003). Higher frequencies of chromosome aberrations, sister chromatid exchanges, and micronuclei have been observed in peripheral lymphocytes of pesticide applicators and certain groups of farmers (Bolognesi 2003; Maroni and Fait 1993). Because of these chromosome abnormalities, cancers in the hematolymphoid tissues [e.g., non-Hodgkin lymphoma (NHL), Hodgkin lymphoma, multiple myeloma, and leukemia] have been a central issue in the evaluation for potential health consequences of pesticide exposure.…”

“…There have been extensive reviews (Acquavella et al 1998; Dich et al 1997; Maroni and Fait 1993; Morrison et al 1992; Zahm and Ward 1998) on cancer risk associated with farming and pesticide exposure as well as a number of more recent articles on specific types of cancer and specific classes of pesticides (Blair et al 1998; Buckley et al 2000; Cantor et al 2003; Hardell et al 2002; Kogevinas et al 1995; McDuffie et al 2001; Meinert et al 2000; Nanni et al 1996; Schroeder et al 2001; Waddell et al 2001; Woods et al 1987; Zahm et al 1990; Zheng et al 2001). However, the vast majority of those studies have focused only on occupational exposures, except for some childhood cancer studies in which parental exposures in and around the home were assessed (Buckley et al 2000; Meinert et al 2000; Zahm and Ward 1998).…”

Pesticide Product Use and Risk of Non-Hodgkin Lymphoma in Women

“…For instance, occupational exposure to pesticides is often accompanied by exposure to other possible hazardous substances, such as solvents, fuels, and dusts (Maroni and Fait 1993; Morrison et al 1992), that have been associated with increased NHL risk (Mao et al 2000; Rego 1998). Similarly, people who use pesticides in and around the home may tend to use other household chemicals more often than those who do not.…”

“…Furthermore, it has been reported that exposure to certain pesticides synergistically increases the mutagenicity of diet-derived heterocyclic amines (Wagner et al 2003). Higher frequencies of chromosome aberrations, sister chromatid exchanges, and micronuclei have been observed in peripheral lymphocytes of pesticide applicators and certain groups of farmers (Bolognesi 2003; Maroni and Fait 1993). Because of these chromosome abnormalities, cancers in the hematolymphoid tissues [e.g., non-Hodgkin lymphoma (NHL), Hodgkin lymphoma, multiple myeloma, and leukemia] have been a central issue in the evaluation for potential health consequences of pesticide exposure.…”

“…There have been extensive reviews (Acquavella et al 1998; Dich et al 1997; Maroni and Fait 1993; Morrison et al 1992; Zahm and Ward 1998) on cancer risk associated with farming and pesticide exposure as well as a number of more recent articles on specific types of cancer and specific classes of pesticides (Blair et al 1998; Buckley et al 2000; Cantor et al 2003; Hardell et al 2002; Kogevinas et al 1995; McDuffie et al 2001; Meinert et al 2000; Nanni et al 1996; Schroeder et al 2001; Waddell et al 2001; Woods et al 1987; Zahm et al 1990; Zheng et al 2001). However, the vast majority of those studies have focused only on occupational exposures, except for some childhood cancer studies in which parental exposures in and around the home were assessed (Buckley et al 2000; Meinert et al 2000; Zahm and Ward 1998).…”

Multiple Screening of Pesticides Toxicity in Zebrafish and Daphnia Based on Locomotor Activity Alterations

“…A single clone of tested daphnia was obtained by parthenogenetic reproduction and maintained in 12 L of culture medium under a light-dark period of 14 h: 10 h with a temperature of 20 ± 2 °C and pH 6.7 and a water conductivity between 300 and 1500 µS. The animals were fed by either green alga or beaker yeast suspension and the cultured water was exchanged every two days (≥80%) [ 4 ]. Locomotion activity of daphnia is depended upon the body sizes; therefore, a filter was used to make sure the uniform body size.…”

“…The excessive use of pesticides leads to undesirable consequences to human health and the environment because of their high biological activity and persistence in the environment. Furthermore, inappropriate handling of pesticides may cause severe acute toxicity [ 4 ]. The general population may be exposed to pesticide residues in foods and drinking water [ 5 ].…”

Pesticide Product Use and Risk of Non-Hodgkin Lymphoma in Women

“…For instance, occupational exposure to pesticides is often accompanied by exposure to other possible hazardous substances, such as solvents, fuels, and dusts (Maroni and Fait 1993; Morrison et al 1992), that have been associated with increased NHL risk (Mao et al 2000; Rego 1998). Similarly, people who use pesticides in and around the home may tend to use other household chemicals more often than those who do not.…”

“…Furthermore, it has been reported that exposure to certain pesticides synergistically increases the mutagenicity of diet-derived heterocyclic amines (Wagner et al 2003). Higher frequencies of chromosome aberrations, sister chromatid exchanges, and micronuclei have been observed in peripheral lymphocytes of pesticide applicators and certain groups of farmers (Bolognesi 2003; Maroni and Fait 1993). Because of these chromosome abnormalities, cancers in the hematolymphoid tissues [e.g., non-Hodgkin lymphoma (NHL), Hodgkin lymphoma, multiple myeloma, and leukemia] have been a central issue in the evaluation for potential health consequences of pesticide exposure.…”

“…There have been extensive reviews (Acquavella et al 1998; Dich et al 1997; Maroni and Fait 1993; Morrison et al 1992; Zahm and Ward 1998) on cancer risk associated with farming and pesticide exposure as well as a number of more recent articles on specific types of cancer and specific classes of pesticides (Blair et al 1998; Buckley et al 2000; Cantor et al 2003; Hardell et al 2002; Kogevinas et al 1995; McDuffie et al 2001; Meinert et al 2000; Nanni et al 1996; Schroeder et al 2001; Waddell et al 2001; Woods et al 1987; Zahm et al 1990; Zheng et al 2001). However, the vast majority of those studies have focused only on occupational exposures, except for some childhood cancer studies in which parental exposures in and around the home were assessed (Buckley et al 2000; Meinert et al 2000; Zahm and Ward 1998).…”

Multiple Screening of Pesticides Toxicity in Zebrafish and Daphnia Based on Locomotor Activity Alterations

“…A single clone of tested daphnia was obtained by parthenogenetic reproduction and maintained in 12 L of culture medium under a light-dark period of 14 h: 10 h with a temperature of 20 ± 2 °C and pH 6.7 and a water conductivity between 300 and 1500 µS. The animals were fed by either green alga or beaker yeast suspension and the cultured water was exchanged every two days (≥80%) [ 4 ]. Locomotion activity of daphnia is depended upon the body sizes; therefore, a filter was used to make sure the uniform body size.…”

“…The excessive use of pesticides leads to undesirable consequences to human health and the environment because of their high biological activity and persistence in the environment. Furthermore, inappropriate handling of pesticides may cause severe acute toxicity [ 4 ]. The general population may be exposed to pesticide residues in foods and drinking water [ 5 ].…”

Pesticide Product Use and Risk of Non-Hodgkin Lymphoma in Women

“…For instance, occupational exposure to pesticides is often accompanied by exposure to other possible hazardous substances, such as solvents, fuels, and dusts (Maroni and Fait 1993; Morrison et al 1992), that have been associated with increased NHL risk (Mao et al 2000; Rego 1998). Similarly, people who use pesticides in and around the home may tend to use other household chemicals more often than those who do not.…”

“…Furthermore, it has been reported that exposure to certain pesticides synergistically increases the mutagenicity of diet-derived heterocyclic amines (Wagner et al 2003). Higher frequencies of chromosome aberrations, sister chromatid exchanges, and micronuclei have been observed in peripheral lymphocytes of pesticide applicators and certain groups of farmers (Bolognesi 2003; Maroni and Fait 1993). Because of these chromosome abnormalities, cancers in the hematolymphoid tissues [e.g., non-Hodgkin lymphoma (NHL), Hodgkin lymphoma, multiple myeloma, and leukemia] have been a central issue in the evaluation for potential health consequences of pesticide exposure.…”

“…There have been extensive reviews (Acquavella et al 1998; Dich et al 1997; Maroni and Fait 1993; Morrison et al 1992; Zahm and Ward 1998) on cancer risk associated with farming and pesticide exposure as well as a number of more recent articles on specific types of cancer and specific classes of pesticides (Blair et al 1998; Buckley et al 2000; Cantor et al 2003; Hardell et al 2002; Kogevinas et al 1995; McDuffie et al 2001; Meinert et al 2000; Nanni et al 1996; Schroeder et al 2001; Waddell et al 2001; Woods et al 1987; Zahm et al 1990; Zheng et al 2001). However, the vast majority of those studies have focused only on occupational exposures, except for some childhood cancer studies in which parental exposures in and around the home were assessed (Buckley et al 2000; Meinert et al 2000; Zahm and Ward 1998).…”

Multiple Screening of Pesticides Toxicity in Zebrafish and Daphnia Based on Locomotor Activity Alterations

“…A single clone of tested daphnia was obtained by parthenogenetic reproduction and maintained in 12 L of culture medium under a light-dark period of 14 h: 10 h with a temperature of 20 ± 2 °C and pH 6.7 and a water conductivity between 300 and 1500 µS. The animals were fed by either green alga or beaker yeast suspension and the cultured water was exchanged every two days (≥80%) [ 4 ]. Locomotion activity of daphnia is depended upon the body sizes; therefore, a filter was used to make sure the uniform body size.…”

“…The excessive use of pesticides leads to undesirable consequences to human health and the environment because of their high biological activity and persistence in the environment. Furthermore, inappropriate handling of pesticides may cause severe acute toxicity [ 4 ]. The general population may be exposed to pesticide residues in foods and drinking water [ 5 ].…”