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Ji-Xiao Wang, et al. 2015
Journal of Coordination Chemistry volume 68, issue 9, P1544-1558

L1 = 1,4-bis((1H-pyrazol-1-yl)methyl)benzene; L2 = 1,4-bis((3,5-dimethyl-1H-pyrazol-1-yl)methyl)benzene... ; H 2 dipic = 2,6-pyridinedicarboxylic acid), were synthesized by reaction of copper salt, arene-linked... pyrazolyl methane ligands and 2,6-pyridinedicarboxylic acid in 95% C 2 H 5 OH.... They were characterized by elemental analysis, IR, UV-Vis, single crystal X-ray diffraction analysis,... application of the copper complexes in bromination reactions; the complexes exhibited bromination catalytic activity

Kiran S. Hon, et al. 2020
J Heterocycl Chem volume 57, issue 4, P1692-1697

Abstract Novel 1benzyl‐3‐(4‐fluorophenyl)‐1H‐pyrazole‐4‐carbaldehydes 3a to 3e were synthesized via... Vilsmeier‐Haack reaction of the appropriate 1benzyl2‐(1‐(4‐fluorophenyl)ethylidene)hydrazines, derived... 1‐(4‐fluoro‐2‐hydroxyphenyl)ethanone 4 gave (E)‐3‐(1benzyl‐3‐(4‐fluorophenyl)‐1H‐pyrazol‐4‐yl)‐1‐(4... On cyclization with dimethyl sulfoxide (DMSO)/I2, compounds 5a to 5e gave 2‐(1benzyl‐3‐(4‐fluorophenyl... All the synthesized compounds were screened for their antibacterial activities.

Mohamed hassan, et al. 2019
Egypt. J. Chem. volume 0, issue 0, P0-0

6'-amino-2'-(dicyanomethylene)-2-oxo-2',3'-dihydro-1'H-spiro[indoline-3,4'-pyridine]-3',5'-dicarbonitrile... 6a, 2'-(dicyanomethylene) 2,6'-dioxospiro[indoline-3,4'-piperidine]-3',5'-dicarbonitrile 6b and 2-(5... '-acetyl-3'-cyano-6'-methyl-2-oxo-1'Hspiro[indoline-3,4'-pyridin]-2'(3'H) ylidene) malononitrile 7, respectively... )-5-((5,5-dimethyl-3-oxocyclohex-1-en-1-yl)amino)-1H-pyrazole-4carbonitrile 11 and 2-(cyano(2-oxoindolin... The antibacterial activities of the synthesized compounds were evaluated.

K. Indrasena Reddy, et al. 2017

All these compounds were characterized by IR, H NMR,C NMR and mass spectral data.... Among the screened compounds, N-(3-isopropoxy-1-isopropyl-4-(3,5-dimethyl-1H-pyrazol-1-yl)-1H-pyrazol... -5-yl)cyclobutane carboxamide and N-(5'-Isopropoxy-2'-isopropyl-3,5-dimethyl-2'H-[1,4'] bipyrazolyl-3... 3-isopropoxy-1-isopropyl-4-(3,5-dimethyl-2H-pyrrol-2-yl)-1H-pyrazol-5-yl)benzamide and 2,6-difluoro-N... -(3-isopropoxy-1-isopropyl-4-(3,5-dimethyl-2H-pyrrol-2-yl)-1H-pyrazol-5-yl) benzamide were found to be

Renu Sharma, et al. 2009

AbstractThe reaction of cobalt(II) chloride with a new class of thiosemicarbazones viz; cis-3,7-dimethyl... -2,6-octadienthiosemicarbazone(CDOTSC; L 1 H) and 3,7-dimethyl-6-octenethiosemicarbazone (DOTSC; L 2... H) and N-phthaloyl derivative of DL-glycine(A 1 H), L-alanine(A 2 H) or L-valine(A 3 H) in 1:1:1 molar... ratio in dry refluxing ethanol have been studied.... Attempts have been made to establish a correlation between the antibacterial and antifungal activity

A.M. Khalil, et al. 2009
European Journal of Medicinal Chemistry volume 44, issue 11, P4448-4454

3-(1,4-Dioxo-3,4,4e,5,10,10a-hexahydro-1H-5,10-benzeno-benzo[g]phthalazin-2-yl)-3-oxo-propiononitrile... (1) was utilized as key intermediate for the synthesis of some new iminocoumarin 2, chromenone 3, aminothiazole... 10 quinoxaline 11, ketene N,S-acetal 13, ketene S,S-diacetal 17 and 18a, b and methyl dithioate 20 derivatives... The newly synthesized compounds were characterized by IR, (1)H NMR, (13)C NMR and mass spectral studies... Representative compounds of the synthesized product were tested and evaluated as antibacterial agent.

A. Bakalova, et al. 2013
Drug Res (Stuttg) volume 63, issue 08, P420-423

The novel compounds were characterized by elemental analysis, IR, 1H, 13C, NMR spectra in solid state... of Pt(IV) with other derivatives like 3-amino-5-methyl-5-(4-pyridyl)hydantoin (1), 5-methyl-5-(4-pyridyl... )hydantoin (2), 3,5-dimethyl-5-(4-pyridyl)hydantoin (3) was screened against a panel of human tumor cell... concentration, though the activity of the other studied Pt(IV) complexes proved to greatly decrease... in the order 5-4-3-2-1.

R. Rajkumar, et al. 2014
Journal of Saudi Chemical Society volume 18, issue 5, P735-743

A simple, highly useful synthesis of 1-(2-(4,5-dimethyl-2-phenyl-1H-imidazol-1-yl)ethyl)piperazine derivatives... is achieved by a four component cyclo condensation of diacetyl, aromatic aldehyde, 2-(piperazin-1-yl... The synthesized compounds were characterized by IR, 1 H and 13 C NMR and mass spectral studies.... Among the newly synthesized compounds 5d, 5e, 5h and 5m showed excellent antibacterial and antifungal... activities when compared to the standard drugs.ª 2014 Production and hosting by Elsevier B.V. on behalf

Hasan Erdinç SELLİTEPE, et al. 2019
jrp volume 23, issue 4, P608-616

The aim of this study is to synthesize and characterize 4-aryl-1,4-dihydropyridine derivatives and evaluate... The structure of the synthesized compounds were characterized by IR and 1 H-NMR spectral studies.... Antioxidant studies of the synthesized compounds were performed by measuring the 1,1-diphenyl-2-picrylhydrazyl... Results showed that 4-bromo substituted derivative (1b) has the highest antioxidant activity compared... In this study, eight 1,4-dihydropyridine derivatives, dimethyl 4-(phenyl/substituted phenyl)-2,6-dimethyl

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