Вопросы Хирургического Лечения Хронического Тонзиллита

Михайлов, Ю.Х.; Михайлова, И.В.

doi:10.18411/spc-18-01-2018-09

Cited by 2 publications

(3 citation statements)

References 2 publications

(2 reference statements)

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“…Помимо того, в нашей работе выявлена стойкая тенденция к меньшей частоте рубцовых осложнений более чем в 2 раза (на 57%) в группе пациентов, принимавших Флогэнзим® (6% против 12,7% -в контрольной). Частота встречаемости послеоперационных стриктур сопоставима с результатами других авторов [30]. Стоит отметить, что часть пациентов контрольной группы с субкомпенсированными стриктурами воздержались от повторной операции и решили продолжить динамическое наблюдение, не осознавая риски дисфункции мочевого пузыря в дальнейшем (в основной группе коррекция рубцовых осложнений проведена всем 3 пациентам, в контрольной -4 из 7).…”

Section: материалы и методыunclassified

Efficacy of Phlogenzyme® in men following transurethral laser enucleation of prostate hyperplasia: results of a randomized trial

Kotov,

Pulbere,

Yusufov

et al. 2024

Vestn. Urol.

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Introduction. The most advanced and eﬀective method of surgical treatment for benign prostatic hyperplasia (BPH) is transurethral laser enucleation of the prostate (tLEP). Recently, there has been a growing interest in exploring new approaches to reduce the risk of complications following tLEP.Objective. To evaluate the eﬃcacy of using Phlogenzym® as part of a comprehensive treatment plan for patients following tLEP to reduce dysuria (urinary discomfort), leukocyturia (white blood cells in urine), and prevent infectious and ﬁbrosis-related complications.Materials & methods. An open-label, randomized trial enrolled 105 patients undergoing tLEP. The patients were randomly assigned to two groups: the study group (n=50) received standard postoperative care in combination with Phlogenzym® for 30 days, while the control group (n=55) received standard care (α1-adrenergic blocker for 28 days) only. uring the follow-up period, which lasted for 1, 3, and 6 months postoperatively, complaints were evaluated using the IPSS-QoL, and IIEF-5 questionnaires, as well as indicators of urinalysis and urine culture, prostate volume measurements, residual urine volume, and uroﬂowmetry data.Results. Among all patients, the median preoperative values for prostate volume, IPSS, QoL score, and median peak urine ﬂow rate were 90 cc, 18 points, 5 points, and 7.9 mL/s, respectively, with no signiﬁcant diﬀerences between the groups. One month after surgery, in the study group, there was a more signiﬁcant decrease in prostate volume (57% vs. 41%), although this diﬀerence was not statistically signiﬁcant (p > 0.05). At the 6-month follow-up, bacteriuria was less common in the study group (42% vs. 67%), and there was a consistent trend toward a reduction in the incidence of ﬁbrous complications, although these diﬀerences were not statistically signiﬁcant either (p > 0.05). No adverse events occurred during the follow-up period.Conclusion. Our experience suggests that the use of Phlogenzym® is safe during the postoperative period following tLEP surgery. The use of this drug leads to a reduction in prostate volume postoperatively and signiﬁcantly reduces the bacteriuria by the six-month follow-up. Additionally, there is a persistent positive trend towards reducing the overall incidence of ﬁbrotic complications in the surgical site. The results achieved and the absence of signiﬁcant side eﬀects characterize Phlogenzym® as having a favorable clinical proﬁle.

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Section: материалы и методыunclassified

Efficacy of Phlogenzyme® in men following transurethral laser enucleation of prostate hyperplasia: results of a randomized trial

Kotov,

Pulbere,

Yusufov

et al. 2024

Vestn. Urol.

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“…5. Регион, в котором расположена рассматриваемая дельта, относится к области недостаточного увлажнения, что типично для бóльшей части умеренного климатического пояса, поэтому водный баланс рассматриваемой дельты отрицательный [5,7]. Если по результатам гидравлического расчета окажется, что объем стока, поступающего по протоку в озеро в многоводную фазу, превышает объем стока, возвращающегося в рукав в маловодную фазу, то это должно быть объяснено влиянием видимого испарения с озера (разности испарения с его поверхности и атмосферных осадков).…”

Section: гидравлический расчет внутреннего водообмена в абстрактной с...unclassified

“…Подобные процессы характерны и для других дельт [7]. В условиях недостаточного увлажнения в регионе годовой водный баланс дельт от-рицательный, как в дельтах Терека [8], Урала [8], Кубани [3].…”

Section: гидравлический расчет внутреннего водообмена в абстрактной с...unclassified

Internal and external water exchange in nontidal river estuaries

Mikhailova,

Isupova

2019

Водные ресурсы

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Вопросы Хирургического Лечения Хронического Тонзиллита

Cited by 2 publications

References 2 publications

Efficacy of Phlogenzyme® in men following transurethral laser enucleation of prostate hyperplasia: results of a randomized trial

Efficacy of Phlogenzyme® in men following transurethral laser enucleation of prostate hyperplasia: results of a randomized trial

Internal and external water exchange in nontidal river estuaries

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