2007
DOI: 10.1373/clinchem.2006.078980
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Abstract: Background: Little research has been done to examine whether γ-glutamyltransferase (GGT) is prospectively associated with the development of chronic kidney disease (CKD). We performed a prospective study to examine the association between GGT and the risk for the development of CKD. Methods: The study cohort included a total of 10 337 healthy males with normal baseline kidney functions and no proteinuria. Participants were workers in a semiconductor manufacturing company and its 13 affiliates. C… Show more

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Cited by 190 publications
(177 citation statements)
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“…These variables were assessed at each visit. 15 Blood samples were taken from the antecubital vein after 412 h of fasting. Serum levels of glucose, uric acid, total cholesterol, triglyceride, low-density lipoprotein cholesterol, HDL-C, gamma-glutamyltransferase, alanin aminotransferase and aspartate aminotransferase were measured using Bayer Reagent Packs on an automated chemistry analyzer (Advia 1650 Autoanalyzer; Bayer Diagnostics, Leverkusen, Germany).…”
Section: Measurementsmentioning
confidence: 99%
“…These variables were assessed at each visit. 15 Blood samples were taken from the antecubital vein after 412 h of fasting. Serum levels of glucose, uric acid, total cholesterol, triglyceride, low-density lipoprotein cholesterol, HDL-C, gamma-glutamyltransferase, alanin aminotransferase and aspartate aminotransferase were measured using Bayer Reagent Packs on an automated chemistry analyzer (Advia 1650 Autoanalyzer; Bayer Diagnostics, Leverkusen, Germany).…”
Section: Measurementsmentioning
confidence: 99%
“…During follow-up, 4,884 (5.3%) incident cancers were observed. On average, 3.8 GGT measurements were obtained for each participant (range [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19]. Baseline GGT levels ranged from 3.0 to 590.7 U/L, with a median of 17.9 U/L.…”
Section: Characteristics Of Study Populationmentioning
confidence: 99%
“…Particularly, GGT was independently related to cardiovascular disease, [5][6][7][8][9][10][11][12] it correlated with most cardiovascular risk factors [13][14][15][16] and, more recently, an association with chronic kidney disease was found. 17 In addition, several large-scale studies indicate an independent role of GGT for premature death from all causes. 9,18,19 The association of GGT with cancer incidence, however, remains largely unexplored.…”
mentioning
confidence: 99%
“…44 The study population included workers who were Ն40 yr of age and underwent an annual comprehensive health examination and workers who were 30 to 39 yr of age and underwent a biennial comprehensive health examination. In 2002, 15,347 workers aged 30 to 59 yr participated in the comprehensive health examinations at a university hospital in Seoul, Korea.…”
Section: Study Populationmentioning
confidence: 99%