2021
DOI: 10.1111/jcmm.17060
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Abstract: Spectrin is the main component of the cytoskeleton and includes α-spectrin (α1, α2) and β-spectrin (β1-5). βII spectrin (β2SP) is encoded by Sptbn1, and it consists of two tandem calponin homology domains (CH1 and CH2), and both contains one actin-binding domain (ABD) in the amino-terminus. 1 β2SP is involved in the regulation of various cell functions, such as proliferation, blood vessel formation and immune response. 2 More recently, β2SP has been linked to multiple signalling pathways, including cell cycle … Show more

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