β-tricalcium phosphate nanoparticles adhered carbon nanofibrous membrane for human osteoblasts cell culture

Liu, Haiyang; Cai, Qing; Lian, Pengfei; Zhou, Fang; Duan, Shun; Yang, Xiaoping; Deng, Xuliang; Ryu, Seung‐Kon

doi:10.1016/j.matlet.2009.12.050

Cited by 29 publications

(24 citation statements)

References 8 publications

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“… Tibia [ 39 ] and femora [ 45 ] of rabbits; alveolar sockets of human [ 46 ]. OCP Murine fibroblasts [ 47 ]; rat bone marrow cells [ 48 ]; human osteoblast cells [ 49 ] Crania [ 50 , 51 ], calvaria and tibia of rats [ 52 , 53 ]; α-TCP Newborn mouse calvaria-derived osteoblast cells [ 54 ]; human: osteoblast-like cells [ 55 ], primary osteoblasts, bone marrow mesenchymal cells and non-adherent myelomonocytic cells [ 56 ]; Tibial head of minipigs [ 57 ]; cranial bone [ 58 ] and calvaria [ 59 ] of rabbits; β-TCP Mouse osteoblast cells [ 60 ]; human: osteoblast cells [ 61 , 62 ], fibroblasts and umbilical vein endothelial cells [ 63 ]; Calvaria of Rats [ 64 ]; tibia of goats [ 65 , 66 ]. ACP Mg 2+ stabilized nanospheres: mouse osteoblast cells [ 67 ].…”

Section: Different Types Of Calcium Phosphatesmentioning

confidence: 99%

Biofunctionalization of metallic implants by calcium phosphate coatings

Cockerill

Zheng

et al. 2019

Bioactive Materials

182

105

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Metallic materials have been extensively applied in clinical practice due to their unique mechanical properties and durability. Recent years have witnessed broad interests and advances on surface functionalization of metallic implants for high-performance biofunctions. Calcium phosphates (CaPs) are the major inorganic component of bone tissues, and thus owning inherent biocompatibility and osseointegration properties. As such, they have been widely used in clinical orthopedics and dentistry. The new emergence of surface functionalization on metallic implants with CaP coatings shows promise for a combination of mechanical properties from metals and various biofunctions from CaPs. This review provides a brief summary of state-of-art of surface biofunctionalization on implantable metals by CaP coatings. We first glance over different types of CaPs with their coating methods and in vitro and in vivo performances, and then give insight into the representative biofunctions, i.e. osteointegration, corrosion resistance and biodegradation control, and antibacterial property, provided by CaP coatings for metallic implant materials.

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Section: Different Types Of Calcium Phosphatesmentioning

confidence: 99%

Biofunctionalization of metallic implants by calcium phosphate coatings

Cockerill

Zheng

et al. 2019

Bioactive Materials

182

105

View full text Add to dashboard Cite

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“…The structural integrity of CNFs was usually deteriorated by covalently/noncovalently decorated inorganic nanoparticles. [13][14][15][16] In comparison with cases of introducing M or MO x nanoparticles into electrospinning PAN solution directly, the electrospinning/sol-gel technique produced CNF/M or CNF/MO x composites conquered the disadvantage of serious aggregation of nanoparticles in the solution and in resulting nanobers. [8][9][10][11] The process showed advantages of catalyst-free preparation and strong exibility in tailoring the strength and elastic modulus of CNFs by regulating the carbonization temperatures and alignment degrees.…”

Section: Introductionmentioning

confidence: 99%

“…6,7 Polyacrylonitrile (PAN)-based CNFs produced from solution electrospinning, pre-oxidation and carbonization have provided a feasible way to modify CNFs and improve the performances of currently available CNFs. [13][14][15][16] Materials including CNF/b-TCP, 13 22,23 had been intensively studied as photocatalyst, Liion battery anode, energy storage container and bone tissue regeneration substrate, etc. 12 By dissolving organic precursors of metal/metal oxide into the electrospinning PAN solution, CNF/M or CNF/MO x composites could be readily prepared.…”

Section: Introductionmentioning

confidence: 99%

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Growth mechanism of bioglass nanoparticles in polyacrylonitrile-based carbon nanofibers

et al. 2014

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Polyacrylonitrile (PAN) electrospinning in combination with sol-gel method has been a common technique to produce inorganic nanoparticles containing composite carbon nanofibers (CNFs) for diverse applications. To investigate the morphology evolution and crystal transformation of inorganic components along with CNF formation, bioactive glass (BG) containing CNFs (CNF/BG) were prepared by sintering as-spun PAN/precursor composite nanofibers in a nitrogen atmosphere at temperatures of 800, 1000 and 1200 C. Comprehensive characterizations were performed with TEM, SEM-EDXA and XRD. For samples sintered at 800 C, numerous BG nanoparticles were observed inside the CNFs and mainly in an amorphous state. With the sintering temperature raised to 1000 C, a number of spherical BG nanoparticles were detected on the surface of the resulting CNFs, with a crystal structure of wollastonite (b-CaSiO 3 ) polycrystals. When the samples were sintered at 1200 C, the BG nanoparticles on the surface of CNFs merged into forms with cuboid-like geometry, mainly consisting of pseudowollastonite (Ca 3 (Si 3 O 9 )) single crystals. Based on the geometry evolution and dynamic size distribution function analyses (Ostwald ripening and Smoluchowski equations), it was concluded that the growth of BG nanoparticles conformed to the ripening mechanism at 800 C and migrationcoalescence mechanism at 1200 C, while the process involved both ripening and migrationcoalescence mechanisms at 1000 C.

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“…8 From our previous studies, 6,7,[9][10][11] it was noticed that b-TCP or BG nanoparticles in CNF composites could be either located on the fiber surface or inside fibers. The surface area would thus be one important factor to influence the dissolution rate.…”

Section: Introductionmentioning

confidence: 99%

Nanoporous structured carbon nanofiber–bioactive glass composites for skeletal tissue regeneration

et al. 2015

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Bioactive glass (BG) decorated nanoporous composite carbon nanofibers (PCNF-BG) were prepared for the purpose of obtaining effective substrates for skeletal tissue regeneration. The preparation was conducted by electrospinning of polyacrylonitrile (PAN)-polymethylmethacrylate (PMMA) blends with the addition of sol-gel precursors of 58s-type (mol%: 58% SiO 2 -38% CaO-4% P 2 O 5 ) BG, followed by high temperature thermal treatment. The removal of PMMA during the carbonization of PAN generated numerous slit-like nanoporous structures along CNFs, leading to a significant enhancement in the specific surface area, surface roughness and pore volume, which was confirmed by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Brunauer-Emmett-Teller (BET) characterizations. PCNF-BG composites with different specific surface areas were biologically evaluated by experiments of biomineralization in simulated body fluid (SBF), in vitro MC3T3-E1 osteoblast proliferation and osteogenic differentiation. Compared to non-porous CNF/ BG, the nanoporous structure distinctively enlarged the interfacial reaction area of the BG component with a medium environment and thus enhanced the bioactivity of CNFs by accelerating the dissolution of the BG component and providing abundant nucleation sites for hydroxyapatite depositions. The released ions displayed distinct promotion in proliferation and osteogenic differentiation of osteoblast cells, which promoted the osteocompatibility of carbon-based materials significantly.Fig. 10 ALP activity expression of MC3T3-E1 cultured on TCPS, pure CNFs and PCNF-BG composites for various times. The results are represented as mean AE standard deviation for n = 3 (p o 0.05).Fig. 9 SEM images showing the morphologies of MC3T3-E1 osteoblasts cultured on pure CNFs and PCNF-BG composites for various times.

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β-tricalcium phosphate nanoparticles adhered carbon nanofibrous membrane for human osteoblasts cell culture

Cited by 29 publications

References 8 publications

Biofunctionalization of metallic implants by calcium phosphate coatings

Biofunctionalization of metallic implants by calcium phosphate coatings

Growth mechanism of bioglass nanoparticles in polyacrylonitrile-based carbon nanofibers

Nanoporous structured carbon nanofiber–bioactive glass composites for skeletal tissue regeneration

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