Β-Sitosterol-3-O-β-D-xylopyranoside from the flowers ofTridax procumbens Linn

Saxena, Vipin; Albert, Sosanna

doi:10.1007/bf02709296

Cited by 36 publications

(25 citation statements)

References 11 publications

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“…There are some weeds used for human consumption [1] and cattle fodders. Weeds have high pharmaceutical values [2] such as Tridax procumbens have antimicrobial [3,4], antiseptic, insecticidal, parasiticidal [5], and anticancerous activity [6] as its rich in secondary metabolites.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Analysis of Different Parts Extract in Different Solvent System of a Waste Weed - Calotropis Procera.

Kar

Pattanaik

Pattnaik

et al. 2018

Asian J Pharm Clin Res

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Objective: In the current study, we have focused on the major secondary metabolite containing parts such as flower, leaf, and root for phytochemical extraction with three different solvent systems to make a comparative study against three virulent bacteria species which are capable of intestinal infection, pneumonia, skin infections, and food poisoning.Methods: Antimicrobial activity of ethanol, methanol, and chloroform extracts from bark, leaves and roots of Calotropis procera, was examined against three virulent bacteria species: Escherichia coli, Staphylococcus aureus, and Bacillus subtilis using disc diffusion method. Results:The ethanol extract of leaf showed significant activity against S. aureus with a zone of inhibition ranging from 14 to 20 mm for S. aureus. The ethanol extract of flower was effective against E. coli with maximum 18 mm. Ethanol extract of root showed significant activity against S. aureus. Methanol extract of leaves showed moderate activity against S. aureus with a zone of inhibition ranging from 14 to 20 mm. Methanol extract of root showed significant activity against S. aureus with a zone of inhibition ranging from 12 to 22 mm. Methanol extract of flowers showed activity against E. coli with a zone of inhibition ranging from 11 to 20 mm. The chloroform extract of leaves showed significant activity against S. aureus. Chloroform extract of flower showed activity with zone of inhibition ranging from 11 to 17 mm for S. aureus chloroform extract of root showed activity against E. coli with zone of inhibition ranging from 9 to 17 mm. Conclusion:From the above study, it can be concluded that the activity of the plant extract may be due to the secondary metabolites or broadspectrum antibiotic compounds present in it.

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Section: Introductionmentioning

confidence: 99%

Antimicrobial Analysis of Different Parts Extract in Different Solvent System of a Waste Weed - Calotropis Procera.

Kar

Pattanaik

Pattnaik

et al. 2018

Asian J Pharm Clin Res

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“…is a family of Asteraceae, and its common name includes coat buttons and tridax daisy in English, cadillo chisaca in Spanish, herbe caille in French, ghamra in Hindi (Saxena and Albert, 2005) and kotobukigiku in Japanese. This plant is native of tropical America and naturalized in tropical Africa, Asia, Australia and India.…”

Section: Introductionmentioning

confidence: 99%

Vasorelaxant effects of aqueous leaf extract of <i>Tridax procumbens</i> on aortic smooth muscle isolated from the rat

Salahdeen

Murtala

2012

J. Smooth Muscle Res.

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Tridax procumbens is commonly used in traditional medicine in southern part of Nigeria for the treatment of hypertension. However, the mechanism of its antihypertensive properties remains unclear. Attempts were made to investigate the properties of direct actions of aqueous extract of the leaves of T. procumbens on mechanical responses of smooth muscles in aortic ring preparations isolated from the rat. Endothelium-intact aortic rings, isolated from the normotensive rats, had been pre-contracted with noradrenaline, and cumulative addition of the aqueous extract (0.15-1.05 mg/mL) to the bathing fluid induced a concentration-dependent relaxation. Aqueous extract of T. procumbens also attenuated the contractile responses to KCl and shifted the concentration-response curve to the right. The contractile responses to serotonin were also attenuated and the concentration-response curve was shifted to the right in the presence of the extract. The results of this study indicated that aqueous leaf extract of T. procumbens possesses vasodilatory effects on the aortic smooth muscles isolated from the rat. Based on these results, a possible mechanism involved in the relaxing actions of the extract on vascular smooth muscle was discussed. The results of this study may provide a scientific basis for the use of this extract to the treatment of hypertension in Nigerian traditional medicine.

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“…Some of the compound identified includes lutein, vanillic acid, carotenoids, catechins, quercetin, linolenic, and alpha-linolenic acid [52,53].…”

Section: Discussionmentioning

confidence: 99%

Biochemical parameters as indicators of antihypertensive efficacy of leaf aqueous extract of Tridax procumbens (Lin) in L-NAME induced hypertensive rats

Salahdeen¹,

Salami²,

Paul³

et al. 2017

J Mol Pathophysiol

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Background: Cardiovascular disease is a widespread public health problem and hypertension is one of the major risk factors of it. Tridax procumbens leaf extract is traditionally used in the treatment of hypertension. This study evaluates the effects of T. procumbens extract (TPE) on blood biochemical parameters of N-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats. Materials and Methods: Rats were divided randomly into four different treatment groups. Group I received 0.9% NaCl (control), Group II, III, and IV were given a nitric oxide synthase inhibitor (L-NAME) 40 mg/kg/day, orally for 6 weeks to induce hypertension. Groups III and IV were further treated with TPE (100 and 200 mg/kg/day), respectively, in the past 3 weeks of 6 weeks. Blood pressure, morphological variables, histopathology, plasma lipids, lipoproteins, cholesterol levels, hepatic enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), and other parameters were analyzed. Results: TPE markedly inhibited the sustenance of L-NAME-induced hypertension. This effect was accompanied by a partial or full amelioration of most of the adverse effects induced by L-NAME, such as: (1) Increases in blood pressure, organs weight indices; (2) hyperlipidemia; (3) increased plasma activity of glutamic-pyruvic transaminase (ALT) and AST; and (4) liver and cardiac histological lesions. Conclusions: This study provides evidence about the antihypertensive effects and end-organ protection of TPE in animal model of hypertension. These effects may be due to one or more constitution in this extract.

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Β-Sitosterol-3-O-β-D-xylopyranoside from the flowers ofTridax procumbens Linn

Cited by 36 publications

References 11 publications

Antimicrobial Analysis of Different Parts Extract in Different Solvent System of a Waste Weed - Calotropis Procera.

Antimicrobial Analysis of Different Parts Extract in Different Solvent System of a Waste Weed - Calotropis Procera.

Vasorelaxant effects of aqueous leaf extract of <i>Tridax procumbens</i> on aortic smooth muscle isolated from the rat

Biochemical parameters as indicators of antihypertensive efficacy of leaf aqueous extract of Tridax procumbens (Lin) in L-NAME induced hypertensive rats

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