α-Linolenic acid: Nutraceutical, pharmacological and toxicological evaluation

Sea Buckthorn Oil—A Valuable Source for Cosmeceuticals

“…A decrease in LA level was observed in patients with acne prone skin [8]. The significance of LA and ά-linolenic acid present in SB oil is that these acids cannot be produced by the human body, while other UFAs found in SB oil (GLA, oleic acid, and palmitoleic acid) may in fact be produced by the body under certain conditions [12,31].…”

“…PUFAs present in SB oil are as follows: ά-linolenic acid (ω-3) C18:3 (30 wt %), γ-linolenic acid (ω-6) C18:3 (35.5 wt %), linoleic acid (ω-6) C18:2 (5-7 wt %); while the MUFAs present are as follows: oleic acid (ω-9) C18:1 (14-18 wt %) and eicosanoic acid (ω-9) C20:1 (2 wt %) [8,29,31].…”

“…In comparison to other vegetable oils, SB oil is considered to have a unique composition of carotenoids, fatty acids, and complex lipids [23,31].…”

Acción de flavonoides sobre la conversión de ácidos grasos poliinsaturados de cadena larga a partir de ácidos grasos esenciales

“…Adicionalmente, la incorporación de DHA en los fosfolípidos del tejido nervioso de humanos y modelos animales durante la gestación y la lactancia se asocia con el desarrollo del sistema nervioso y la función visual 6,7 , y su incorporación depende principalmente de la transferencia a través de la placenta y leche materna, respectivamante 6 . La provisión de EPA y DHA a través de la explotación de recursos marinos, no es sostenible 8 , en este contexto, se ha propuesto la obtención de estos ácidos grasos a partir de ALA, considerando que es precursor de EPA y DHA 9 , sin embargo la eficiencia de este proceso es limitada: en humanos la tasa de conversión de ALA hacia EPA es menor al 8%, mientras la conversión de ALA hacia DHA es inferior a 4% 10 . Ciertos antioxidantes interactúan con el metabolismo lipídico, así el consumo de flavonoides como las antocianinas aumenta la actividad y expresión génica de PPAR-α en ratas obesas 11 y disminuye la expresión de SREBP 1c 12 .…”

Quality evaluation of peony seed oil spray-dried in different combinations of wall materials during encapsulation and storage

“…Recent studies demonstrated that the peony seeds are notable for its high oil content, which varies from 24.12 to 37.83 %, and contains more than 90 % unsaturated fatty acids, especially α-linolenic acid (31.56~66.85 %) (Zhang et al 2015). It is well known as that α-Linolenic acid (ALA) as the precursor of EPA (eicosapentaenoic acid,20:3n-5) and DHA (docosahexaenoic acid,, is an essential fatty acid that humans cannot synthesize and must be supplied by diet (Kim et al 2014). These two omega-3 fatty acids serve positive physiologic roles, especially during fetal and infant growth, in the prevention of cardiovascular diseases, and in their effects against inflammation, platelet aggregation, hypertension, and hyperlipidemia (Kaur et al 2014;Lorente-Cebrián et al 2013).…”