Zur Kenntniss der einfachsten Chloräther

Wedekind, E.

doi:10.1002/cber.19030360211

Cited by 5 publications

(2 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The first step, consisting of the removal of the MOM group by HCl, leads to the formation of a methoxymethylene cation 9a. Then, this carbocation reacts with water in acidic medium to give methoxymethanol by releasing HX (Scheme , Equation 1), In the presence of any acid (H + X – ), this molecule decomposes into methanol and formaldehyde 9b. In the early eighties, Bigi proposed a mechanism in which phenol in the presence of formaldehyde formed a methylene‐bridged dimer 9c.…”

Section: Resultsmentioning

confidence: 99%

Facile Formation of Methylenebis(chalcone)s through Unprecedented Methylenation Reaction. Application to Antiparasitic and Natural Product Synthesis

Thévenin¹,

Mouray²,

Grellier³

et al. 2014

Eur J Org Chem

View full text Add to dashboard Cite

The formation of methylenebis(chalcone)s has been discovered during deprotection with methoxymethyl groups from trihydroxychalcones. Studies on this methylenation reaction led to a mechanism hypothesis that was extended to other chalcones and to dihydrochalcone, acetophenone, benzophenone and flavone derivatives. This new method was applied to the rapid synthesis of natural product piperanduncin C. These original methylenebis compounds were also evaluated for their antiparasitic activity.

show abstract

Section: Resultsmentioning

confidence: 99%

Facile Formation of Methylenebis(chalcone)s through Unprecedented Methylenation Reaction. Application to Antiparasitic and Natural Product Synthesis

Thévenin¹,

Mouray²,

Grellier³

et al. 2014

Eur J Org Chem

View full text Add to dashboard Cite

show abstract

“…Chloromethylation of alcohols with dry HCl gas and s ‐trioxane (as a formaldehyde source) is the classical method23 for the preparation of the important protecting group precursors MEM and MOM chloride 24. Unfortunately, this procedure turned out to be incompatible with all three of the protecting groups described above.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of an Intramolecular Approach for the Synthesis of the Elusive C₅₈N₂ Heterofullerene Family

2008

View full text Add to dashboard Cite

A new approach towards the synthesis of the elusive heterofullerene C 58 N 2 is presented. The synthetic strategy is based on the intramolecular 1,3-dipolar cycloaddition of a spacerlinked azide to a monoazaheterofullerene (C 59 N) core. Since this cycloaddition can theoretically result in 16 different isomeric products, the design of the spacer moiety was based on extensive molecular modelling. Two fundamental synthetic routes towards suitably functionalized C 59 N derivatives were designed and carried out. Subsequent one-pot experiments, each making use of the same conditions as had previously

show abstract

Über Chlormethylsulfat

Houben¹,

R.²

1907

Ber. Dtsch. Chem. Ges.

View full text Add to dashboard Cite

Zur Kenntniss der einfachsten Chloräther

Cited by 5 publications

References 2 publications

Facile Formation of Methylenebis(chalcone)s through Unprecedented Methylenation Reaction. Application to Antiparasitic and Natural Product Synthesis

Facile Formation of Methylenebis(chalcone)s through Unprecedented Methylenation Reaction. Application to Antiparasitic and Natural Product Synthesis

Evaluation of an Intramolecular Approach for the Synthesis of the Elusive C₅₈N₂ Heterofullerene Family

Über Chlormethylsulfat

Contact Info

Product

Resources

About

Zur Kenntniss der einfachsten Chloräther

Cited by 5 publications

References 2 publications

Facile Formation of Methylenebis(chalcone)s through Unprecedented Methylenation Reaction. Application to Antiparasitic and Natural Product Synthesis

Facile Formation of Methylenebis(chalcone)s through Unprecedented Methylenation Reaction. Application to Antiparasitic and Natural Product Synthesis

Evaluation of an Intramolecular Approach for the Synthesis of the Elusive C58N2 Heterofullerene Family

Über Chlormethylsulfat

Contact Info

Product

Resources

About

Evaluation of an Intramolecular Approach for the Synthesis of the Elusive C₅₈N₂ Heterofullerene Family