2017
DOI: 10.5155/eurjchem.8.1.66-75.1515 View full text |Buy / Rent full text
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Abstract: A series of 5-substituted and 1,5-disubstituted tetrazoles were synthesized in high yields from various biologically active substituted nitriles with sodium azide under heterogeneous catalysed (ZnBr2-SiO2) [2+3] cycloaddition conditions. This reaction gave an excellent yield in the presence of catalytic amount of 0.2 g of ZnBr2-SiO2, glycerol solvent system under microwave irradiation conditions. All the prepared compounds were characterized by elemental analysis 1 H NMR, 13 C NMR, FT-IR, and mass spectral dat… Show more

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