Zinner syndrome: A first case report from Ethiopia

Beyene, Erko; Tadele, Engidawork; Negassa, Meti

doi:10.1016/j.radcr.2022.09.074

Cited by 4 publications

(4 citation statements)

References 10 publications

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“…Careful evaluation of the imaging studies is crucial to ensure accurate diagnosis and prevent potential misdiagnoses and plan surgical intervention. This approach enables comprehensive assessment and characterization of the genitourinary abnormalities associated with ZS (5). Diagnosing asymptomatic cases is challenging, diagnostics are typically saved for patients with symptoms.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Incidental finding of Zinner syndrome in an asymptomatic 53-year-old Palestinian male

Abu-Hilal,

Barghouthi,

Njoum

et al. 2023

Front. Urol.

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IntroductionZinner syndrome (ZS) is a rare condition characterized by a triad of seminal vesicle cyst (SVC), ipsilateral ejaculatory duct obstruction, and ipsilateral renal agenesis. The diagnosis is often delayed due to non-specific symptoms, such as lower urinary tract symptoms and infertility, typically appearing in the second and third decades of life.Case presentationWe present the first published case of ZS in Palestine, involving a 53-year-old male patient who sought medical attention for right-sided hernia repair. Pre-operative imaging revealed a combination of findings, including a solitary left kidney with cysts, mild hydronephrosis, an enlarged prostate, suspicious soft tissue density, and abnormal lymph nodes. The diagnosis of ZS was confirmed through an abdominal ultrasound, identifying a dilated seminal vesicle and completing the criteria of ZS.DiscussionThe typical for ZS is to present in late second decade of life with nonspecific urogenital symptoms and infertility, However, our patient’s incidental diagnosis during the preoperative evaluation of incisional hernia in a relatively old age with no previous complaints, the identification of a high aortic bifurcation at the level of the left kidney and a double Inferior Vena Cava (IVC) in this case of ZS represents novel and distinctive findings not commonly reported in previous cases.ConclusionOur patient’s presentation and findings expand our understanding of the anatomical variations associated with ZS. This case report contributes to the advancement of knowledge in the field of ZS and provides valuable insights for future clinical management and research investigations.

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Section: Discussionmentioning

confidence: 99%

Case Report: Incidental finding of Zinner syndrome in an asymptomatic 53-year-old Palestinian male

Abu-Hilal,

Barghouthi,

Njoum

et al. 2023

Front. Urol.

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“…Prompt and accurate diagnosis is important to prevent the potential morbidity associated with this condition, such as recurrent epididymitis, urinary tract infections, and infertility [11] . Radiological evaluation can be used to monitor the progression of the cystic lesions and the response to treatment.…”

Section: Discussionmentioning

confidence: 99%

“…Radiological evaluation can be used to monitor the progression of the cystic lesions and the response to treatment. In some symptomatic cases, surgical intervention may be necessary, and radiology is essential for surgical planning and postoperative monitoring [ 11 , 12 ].…”

Section: Discussionmentioning

confidence: 99%

The role of radiology in diagnosis of Zinner syndrome in a young man with scrotal pain

Zare,

Narouie,

Moloudi

et al. 2023

Radiology Case Reports

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“…From these reports, it seems that there are racial differences in the reported incidence of ZS. In Ethiopia, Beyene et al 9 reported that a heightened sexual activity may have contributed to presentation in their case report. This has not been corroborated by other authors.…”

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confidence: 86%

Incidental Zinner Syndrome in Nigeria: A Case Report

Takure,

Adewumi,

Fatade

et al. 2024

EMJ Urol

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Zinner syndrome (ZS) is a rare urogenital condition characterised by the triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ipsilateral ejaculatory duct obstruction, resulting from malformation during early embryogenesis of the mesonephric (Wolffian) duct. The authors present a 35-year-old male who was being evaluated for chronic hepatitis B virus infection. He was referred to the urology outpatient clinic on account of incidental ultrasound finding of solitary right kidney. General physical examination revealed a healthy-looking young male with a flat abdomen and no palpable enlarged organs. Digital rectal examination revealed normal sized prostate with no palpable pararectal masses. MRI of the pelvis revealed a triad of unilateral renal agenesis, ipsilateral seminal vesicle cyst, and ipsilateral ejaculatory duct obstruction. The clinical diagnosis was asymptomatic ZS. He is on yearly follow-up at the urology outpatient clinic for lower urinary tract symptoms, pelvic pain, painful ejaculation, features of infertility, and pelvic ultrasound. If any of these symptoms occur, he will be treated with an α-adrenergic receptor blocker, drainage of the seminal vesicle cyst, and appropriate treatment for infertility. He is also on active surveillance for viral hepatitis by the gastroenterology team. In conclusion, prompt referral and comprehensive radiological imaging investigations of patients with unilateral agenesis of the kidney will lead to increased identification and report of patients with ZS. There is paucity of literature reports on ZS in the authors’ environment, and this case report, to the best of the authors’ knowledge, is the first from Nigeria.

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Zinner syndrome: A first case report from Ethiopia

Cited by 4 publications

References 10 publications

Case Report: Incidental finding of Zinner syndrome in an asymptomatic 53-year-old Palestinian male

Case Report: Incidental finding of Zinner syndrome in an asymptomatic 53-year-old Palestinian male

The role of radiology in diagnosis of Zinner syndrome in a young man with scrotal pain

Incidental Zinner Syndrome in Nigeria: A Case Report

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