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Cited by 129 publications
(130 citation statements)
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“…The range of symptoms and signs in pregnancy is similar to that in non-pregnant adults, (10,26,27) and is equally mild, nonspecific and self-limiting, (28)(29)(30)(31) lasting for a similar duration of 4-6 days. (18) Of note, fever is not a predominant feature of ZIKV infection in symptomatic pregnancies, being present in only 28%-46%; (28)(29)(30) even then, most fevers are very low grade (< 38°C).…”
Section: Is the Clinical Course Of Zikv Infection Different In Pregnamentioning
confidence: 82%
See 2 more Smart Citations
“…The range of symptoms and signs in pregnancy is similar to that in non-pregnant adults, (10,26,27) and is equally mild, nonspecific and self-limiting, (28)(29)(30)(31) lasting for a similar duration of 4-6 days. (18) Of note, fever is not a predominant feature of ZIKV infection in symptomatic pregnancies, being present in only 28%-46%; (28)(29)(30) even then, most fevers are very low grade (< 38°C).…”
Section: Is the Clinical Course Of Zikv Infection Different In Pregnamentioning
confidence: 82%
“…(18) Of note, fever is not a predominant feature of ZIKV infection in symptomatic pregnancies, being present in only 28%-46%; (28)(29)(30) even then, most fevers are very low grade (< 38°C). A maculopapular rash (sometimes pruritic) was the most common symptom affecting 44%-93% of cases, followed by conjunctivitis (36%-58%), myalgia/arthralgia (39%-64%), headache (53%-62%) and lymphadenopathy (about 40%).…”
Section: Is the Clinical Course Of Zikv Infection Different In Pregnamentioning
confidence: 99%
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“…42 Interestingly, a recent article described an infant with congenital ZIKV infection with a chorioretinal scar but without microcephaly. 43 Finally, in addition to the known feature of conjunctivitis mentioned previously, a case of ZIKV-associated uveitis in an adult has been described. 44 There is accumulating evidence that ZIKV infection is associated with Guillain-Barré syndrome (GBS).…”
mentioning
confidence: 77%
“…55 Although there is increasing evidence of a causal link between maternal ZIKV infection, fetal microcephaly, intracranial calcifications, and other CNS and ocular abnormalities, the longterm impact of this pathogen on neurodevelopmental outcomes in affected infants is yet to be fully understood. [58][59][60] Numerous studies have investigated the relationship between maternal infections and neonatal and child outcomes. Severe infections are associated with increased proinflammatory markers, including IL-6, IL-1, and tumor necrosis factor α.…”
Section: The Impact Of Maternal Inflammation On Fetal Neurodevelopmentmentioning
confidence: 99%