Young Ischemic Stroke in South Asia: A review

Ojha, Rajeev; Huang, Dongya; An, Hedi; Zuo, Lian; Zhu, Wenqi

doi:10.3126/jaim.v2i1.7636

Cited by 3 publications

(4 citation statements)

References 60 publications

(75 reference statements)

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“…Moreover, stroke incidence in the younger population has increased globally, with higher consequences physically, psychologically, and socially. Furthermore, other varying risk factors, such as air pollution, obesity, physical inactivity, alcohol consumption, and dyslipidemia, have also increased in the younger population 11–13 . In addition to the younger average age of stroke onset and higher incidence rates, the shift had also changed toward hemorrhagic stroke, which has higher fatality and disability, leading to DALY loss rates up to more than 10‐fold higher than the least affected countries 14 .…”

Section: Stroke Epidemiology In Asiamentioning

confidence: 99%

“…Furthermore, other varying risk factors, such as air pollution, obesity, physical inactivity, alcohol consumption, and dyslipidemia, have also increased in the younger population. [11][12][13] In addition to the younger average age of stroke onset and higher incidence rates, the shift had also changed toward hemorrhagic stroke, which has higher fatality and disability, leading to DALY loss rates up to more than 10-fold higher than the least affected countries. 14 The prevalence of stroke, its risk factors, disability-adjusted life year (DALY), and mortality rate of HOPE Asia Network Countries are shown in Table 1.…”

Section: Introductionmentioning

confidence: 99%

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Hypertension and stroke in Asia: A comprehensive review from HOPE Asia

Turana

Tengkawan

Chia

et al. 2020

J of Clinical Hypertension

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Section: Stroke Epidemiology In Asiamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Hypertension and stroke in Asia: A comprehensive review from HOPE Asia

Turana

Tengkawan

Chia

et al. 2020

J of Clinical Hypertension

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“…Over the last decade, several studies have shown an increase in the number of young stroke patients. However, reports from developing and underdeveloped countries relating to young patients with stroke have been less frequent and were concerned with the higher frequency of undetermined causes of stroke [ 1 – 3 ].…”

Section: Introductionmentioning

confidence: 99%

Distribution of ischemic infarction and stenosis of intra- and extracranial arteries in young Chinese patients with ischemic stroke

Ojha

Huang

et al. 2015

BMC Cardiovasc Disord

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BackgroundThe distribution of cerebral ischemic infarction and stenosis in ischemic stroke may vary with age-group, race and gender. This study was conducted to understand the risk factors and characteristics of cerebral infarction and stenosis of vessels in young Chinese patients with ischemic stroke.MethodsThis was a retrospective study, from January 2007 to July 2012, of 123 patients ≤50 years diagnosed with acute ischemic stroke. Patient characteristics were compared according to sex (98 males and 25 females) and age group (51 patients were ≤45 years and 72 patients were 46–50 years). Characteristics of acute ischemic infarction were studied by diffusion weighted imaging. Stenosis of intra- and extracranial arteries was diagnosed by duplex sonography, head magnetic resonance angiography (MRA) or cervical MRA.ResultsCommon risk factors were hypertension (72.4 %), dyslipidemia (55.3 %), smoking (54.4 %) and diabetes (33.3 %). Lacunar Infarction was most common in our patients (41.5 %). Partial anterior circulation infarction was predominant in females (52.0 vs 32.7 %; P = 0.073) and posterior circulation infarction in males (19.8 vs 4 %; P = 0.073). Multiple brain infarctions were found in 38 patients (30.9 %). Small artery atherosclerosis was found in 54 patients (43.9 %), with higher prevalence in patients of the 46–50 years age-group. Intracranial stenosis was more common than extracranial stenosis, and middle cerebral artery stenosis was most prevalent (27.3 %). Stenosis in the anterior circulation was more frequent than in the posterior circulation (P < 0.001).ConclusionsIn these young patients, hypertension, smoking, dyslipidemia and diabetes were common risk factors. Intracranial stenosis was most common. The middle cerebral artery was highly vulnerable.

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“…Current prevalence estimates for stroke in US younger adults are 0.6% (18-44) and 3.1% (45-64) [6]. The rates of stroke in younger populations may be even higher in developing countries [7].…”

Section: Introductionmentioning

confidence: 99%

Young individuals with stroke in rehabilitation: a cohort study

Campo

Toglia

Jaywant

et al. 2021

International Journal of Rehabilitation Research

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Stroke in younger populations is a public health crisis and the prevalence is rising. Little is known about the progress of younger individuals with stroke in rehabilitation. Characterization of the course and speed of recovery is needed so that rehabilitation professionals can set goals and make decisions. This was a cohort study with data extracted from electronic medical records. Participants were 408 individuals diagnosed with stroke who participated in inpatient rehabilitation in an urban, academic medical center in the USA. The main predictor was age which was categorized as (18–44, 45–64, 65–74 and 75+). Outcomes included baseline-adjusted discharge functional independence measure (FIM) scores and FIM efficiency. In linear regression models for FIM scores, the reference category was the youngest age group. The oldest group was discharged with significantly lower FIM total (B = −8.84), mobility (B = −4.13), self-care (B = −4.07) and cognitive (B = −1.57) scores than the youngest group after controlling for covariates. The 45–64 group also finished with significantly lower FIM total (B = −6.17), mobility (B = −2.61) and self-care (B = −3.01) scores than youngest group. FIM efficiencies were similar for all ages in each of the FIM scales. Younger individuals with stroke make slightly greater functional gains compared to older individuals with stroke, but other factors, such as admission scores, are more important and the rates of recovery may be similar.

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Young Ischemic Stroke in South Asia: A review

Abstract: ABSTRACT

Cited by 3 publications

References 60 publications

Hypertension and stroke in Asia: A comprehensive review from HOPE Asia

Hypertension and stroke in Asia: A comprehensive review from HOPE Asia

Distribution of ischemic infarction and stenosis of intra- and extracranial arteries in young Chinese patients with ischemic stroke

Young individuals with stroke in rehabilitation: a cohort study

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