Yessotoxins in Norwegian blue mussels (Mytilus edulis): uptake from Protoceratium reticulatum, metabolism and depuration

The complete genome sequence of the algal symbiont Dinoroseobacter shibae: a hitchhiker's guide to life in the sea

“…Using PCR with D. shibae-specific primers for the 16S rRNA gene and sequencing of the obtained bands for confirmation, D. shibae was also detected in cultures of Protoceratium reticulatum, a dinoflagellate isolated from the North Sea. All three host species are cosmopolitan, toxic algae causing diarrhetic shellfish poisoning (Aasen et al, 2005). Finally, D. shibae was isolated from Isochrysis galbana, a member of the class Haptophyceae (Genbank accession EF512132).…”

Effects of salinity, temperature and nutrients on growth, cellular characteristics and yessotoxin production of Protoceratium reticulatum

“…reticulatum is common in different geographical areas all over the world and many reports exist about accumulation of YTX in several molluscan shellfish species (e.g. Aasen et al, 2005;Ciminiello et al, 1997Ciminiello et al, , 2003Finch et al, 2005;Krock et al, 2006;MacKenzie et al, 1998;Paz et al, 2004Paz et al, , 2006Paz et al, , 2007Paz et al, , 2008Ramstad et al, 2001;Samdal et al, 2004;Satake et al, 1997Satake et al, , 1999Satake et al, , 2006Suzuki et al, 2007;Yasumoto and Takizawa, 1997). The P. reticulatum strain used in this study was isolated in the North Sea and identified as YTX producer (Hoppenrath, 2004).…”

Towards tailored assays for cell-based approaches to toxicity testing

“…Multiple structural features, however, determine transcriptional responses involving the estrogen receptor system at the level of ligands, receptor forms, and transcriptional co-factors/activators contributing to changes in the transcription of selected genes (see, for instance, Shiau et al, 1998; McKenna duced in the eU (eU, 2011), efforts aimed at the development of cell-based methods has continued, as they are considered of higher value for some purposes. efforts in this area are supported by the recognition that naturally contaminated materials often include many distinct analogues (MacKenzie et al, 2002;Aasen et al, 2005;Dell'Aversano et al, 2008;Rehmann et al, 2008) of varying potency, pinpointing the need to quantify the full series of compounds with toxicological relevance. A second line of intervention recognizes that contamination of seafood by microalgal toxins has been evolving over the years, and novel or atypical contaminations have been detected (Moore and Scheuer, 1971;Hu et al, 1995;Deeds and Schwartz, 2010;ledreux et al, 2012).…”