Infectious Disease Clinics of North America volume 18, issue 2, P275-292 2004 DOI: 10.1016/j.idc.2004.01.007 View full text
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Charles S Bryan, Sandra W Moss, Richard J Kahn

Abstract: Dutch slave traders brought yellow fever to the Americas from Africa during the mid-seventeenth century. For the next two and a half centuries, the disease terrorized seaports throughout the Americas. Proof of the mosquito hypothesis was delayed because of two aspects of the disease: patients are viremic only during the first several days of clinical illness, and most mosquitoes require about 2 weeks of viral incubation before becoming infectious. Control of Aedes aegypti in urban centers failed to eliminate t…

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