Years of Potential Life Lost Due to Breast and Cervical Cancer: a Challenge for Brazilian Public Policy

Gravena, Ângela Andréia França; Brischiliari, Sheila Cristina Rocha; Gil, Laís Moraes; Lopes, Tiara Cristina Romeiro; Demitto, Marcela de Oliveira; Agnolo, Cátia Millene Dell; Borghesan, Deise Helena Pelloso; Carvalho, Maria Dalva de Barros; Pelloso, Sandra Marisa

doi:10.7314/apjcp.2014.15.23.10313

Cited by 4 publications

(4 citation statements)

References 23 publications

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“…In this sense, the trend is that the new cases of the disease diagnosed in advanced stages continue to emerge in younger women [38]. Thus, the clinical protocols and public policies that encourage this form of detection for young women are recommended in Brazil [37].…”

Section: Discussionmentioning

confidence: 99%

The Rise in Mortality from Breast Cancer in Young Women: Trend Analysis in Brazil

et al. 2017

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IntroductionBreast cancer is the most common cause of cancer death among women.ObjectiveThe objective of this study was to analyze time trends in overall mortality from breast cancer in Brazil, Brazilian regions and States.MethodsThis is an exploratory study, of the time series of deaths from breast cancer contained in the Mortality Information System (SIM), of women living in Brazil, Brazilian regions and States, from 1996 to 2013. For the trend analysis, the polynomial regression model was used, and a significant trend was considered when the estimated model obtained a p value <0.05.ResultsThere was a tendency of increased mortality from breast cancer in Brazilian women (average increase of 0.18 per year; p <0.001), with regional differences, particularly in the age group 20–49 years (0.07 per year; p <0.001). The age group 50–69 years remained constant but had high average rates (37.14).ConclusionMore effective planning is needed to focus on the different scenarios of the Brazilian regions. Screening strategies for the incidence and mortality from breast cancer must also be rethought according to age group in the country.

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Section: Discussionmentioning

confidence: 99%

The Rise in Mortality from Breast Cancer in Young Women: Trend Analysis in Brazil

et al. 2017

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“…In addition, a cohort study also stated that in the middle age group (41-50 and 51-60 years) of postmenopausal women, the Luminal B subtype (ER+, PR+/-, HER2-, Ki-67 14-30%) is the most diagnosed breast cancer in this group, while for the age group (61-70 and 71-80 years) most of the patients had the Luminal A subtype (ER+, PR+, HER2-, Ki-67 < 14%) [59]. It can be caused by the increase in fat tissue in the body, especially in postmenopausal women, causing an increase in the secretion of the hormone estrogen which results in an increased risk of invasive breast cancer with positive ER subtype [60][61][62]. Successful therapies for breast cancer, such as chemo-, radio-, and endocrine therapy are known to carry longterm side effects such as cardiotoxicity effects, peripheral neuropathy, arthralgia, muscle strength reduction, musculoskeletal pain, hot flushes, fatigue, depression, dyspareunia, thromboembolic event, and hypercholesterolemia [63][64][65][66][67].…”

Section: Discussionmentioning

confidence: 81%

The Benefits of Physical Activity to Reduce Mortality in Postmenopausal Breast Cancer Patients: A Literature Review

Gumilang

Hernawan

2023

Indonesian Journal of Cancer

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Background: Breast cancer cases are more commonly diagnosed in postmenopausal women and the risk increases with age. Along with an increased vulnerability to breast cancer, increasing age also carries a higher risk of other health problems. Postmenopausal breast cancer patients frequently have one or more pre-existing comorbid conditions at the time of diagnosis. Higher physical activity can reduce breast cancer-specific and overall mortality. However, the vast majority of early breast cancer survivors experience a decrease in physical activity. This study aimed to determine the relationship between physical activity and the reduction of Breast Cancer-Specific Mortality (BCSM) and overall mortality in postmenopausal breast cancer survivors.Methods: This research uses a literature review design by conducting a journal search through Google Scholar, PubMed, and ScienceDirect. The keywords used are (“Physical activity” or Exercise) and (“Breast Cancer” or “Breast Neoplasm”) and (Mortality) and (“Post-menopause”).Results: Seven studies were included in this review. A total of 6276 deaths were reported. Only 3 out of 6 studies reported that there is a significant benefit between physical activity and reduction in breast cancer-specific mortality. Contrarily, all studies reported that there is a significant benefit between physical activity and overall mortality reduction, but at a certain intensity level. Conclusions: Our data suggest that physical activity, whether pre-diagnosis or post-diagnosis, is associated with a better prognosis of breast cancer in postmenopausal women.

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“…20 There is no organized screening in Brazil, but collective mobilization/actions to provide mammography and organized screening models are described. 4,[21][22][23] A collective action to provide mammography performed in the city of Marília (state of São Paulo) yielded 0.84 diagnosed cases/1,000 mammograms. The cost of the mobilization per case diagnosed was considered high, suggesting the superiority of implementing screening services.…”

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confidence: 99%

“…Regarding lost years of life, an increased risk of death from breast cancer was observed in the range of 50-59 years, and a significant increase in the range 40-49 years. 23 Regarding organized screening, we must consider the regional experience in the interior of the state of São Paulo 3,5,24 with a biannual screening proposal in the age range of 40-69 years. In the first two years of the project, 17,964 women were investigated and 76 cases were diagnosed, with an increase in the early stage rate from 14.5% to 43.2%.…”

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Breast cancer screening in Brazil. Barriers related to the health system

Vieira

Formenton

Bertolini

2017

Rev. Assoc. Med. Bras.

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Objective: Identify factors related to the health system that lead to a late diagnosis of breast cancer in Brazil. Method: We performed a systematic review in the PubMed and LILACS databases using as keywords "Breast cancer," "system of health" and "Brazil or Brasil." We evaluated the content of the articles using the PRISMA methodology based on PICTOS. The final date was 12/16/2015. We were able to identify 94 publications in PubMed and 43 publications in LILACS. After assessing the title and summary, and excluding 21 repeated publications, we selected 51 publications for full evaluation. At this stage, we excluded 21 articles, with 30 publications remaining for study. Results: The population coverage is low, and there are problems related to the quality of mammography. Patients with lower income, nonwhite and less educated are more vulnerable. We observed punctual and initial experiences in breast cancer screening. Diagnosis and treatment flows must be improved. The inequality in mortality reflects the differences related to screening structure and treatment. Better results are observed in well-structured services. Conclusion: There are several barriers in the health system leading to advanced stage at diagnosis and limiting the survival outcomes. The establishment of a rapid and effective order for diagnosis and treatment, based on hierarchical flow, are important steps to be improved in the public health context.

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Years of Potential Life Lost Due to Breast and Cervical Cancer: a Challenge for Brazilian Public Policy

Cited by 4 publications

References 23 publications

The Rise in Mortality from Breast Cancer in Young Women: Trend Analysis in Brazil

The Rise in Mortality from Breast Cancer in Young Women: Trend Analysis in Brazil

The Benefits of Physical Activity to Reduce Mortality in Postmenopausal Breast Cancer Patients: A Literature Review

Breast cancer screening in Brazil. Barriers related to the health system

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