Yang/Qi Invigoration: An Herbal Therapy for Chronic Fatigue Syndrome with Yang Deficiency?

Leong, Pou Kuan; Wong, Hoi Shan; Chen, Jihang; Ko, Kam Ming

doi:10.1155/2015/945901

Cited by 49 publications

(27 citation statements)

References 45 publications

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“…The mechanism of yang-xu constitution is pathologically associated with mitochondrial dysfunction [24], impaired thermogenesis [25], or loss of the effectiveness of the pituitary-adrenal axis [26]. Clinical study suggests that T2DM patients with Yang deficiency BC were less likely to present with diabetic retinopathy [5].…”

Section: Discussionmentioning

confidence: 99%

Association of Menopausal Symptoms with Different Constitutions in Climacteric Women

Chen

Hwang

2018

Complement Med Res

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Objective: The aim of this study was to assess the correlation between the body constitution and menopausal symptoms in climacteric women. Methods: This cross-sectional study recruited 427 women aged 40-60 years from the hospital and nearby community. In addition to filling out a questionnaire on menopause rating scale - Traditional Chinese version, the participants completed the body constitution questionnaire. This classifies a person to 1 or more of 3 imbalanced constitutional types, which are yin-xu, yang-xu and stasis-stagnation. We constructed logistic regression models to estimate probabilities of the menopausal symptoms among climacteric women presenting with various menopausal status and differing body constitutions. Results: The frequency and scores of the yin-xu, yang-xu, and stasis-stagnation constitutions were significantly higher in perimenopausal and postmenopausal than premenopausal women. Compared to the non-constitution women, the odds ratio of having hot flushes, sleeping disorders, sexual problems, irritability, and anxiety were significantly higher with the yin-xu constitution. The women with a yang-xu constitution had significantly higher odds ratios for having bladder problems, muscle and joint problems, depressive mood, and heart discomfort. Symptoms of heart discomfort, physical and mental exhaustion, and sleeping disorders were correlated to the stasis-stagnation constitution. Conclusion: With the additional key symptoms related to the 3 constitutional types, physicians performing traditional Chinese medicine (TCM) are able to diagnose the menopausal syndrome more accurately. Integrating menopausal symptoms with TCM constitutional theory will contribute to a more rapid diagnosis and treatment of menopausal syndrome.

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Section: Discussionmentioning

confidence: 99%

Association of Menopausal Symptoms with Different Constitutions in Climacteric Women

Chen

Hwang

2018

Complement Med Res

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“…In general, symptom differentiation is a key component of KM-based diagnosis and treatment. One group proposed the usefulness of symptom differentiation strategy to treat this illness using herbal drugs, such as Cistanches Herba and Schisandrae Fructus for CFS patients with Yang deficiency 37) . A systematic review also reported the possibility of acupuncture or moxibustion as a potential treatment for CFS 38) .…”

Section: New Naming and Perspectives For Cfsmentioning

confidence: 99%

Minireview for Chronic Fatigue Syndrome and its Medical Attention recently

Son

2019

J Korean Med

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Objectives: Chronic fatigue syndrome (CFS) is a debilitating illness impairing seriously quality of life, while CFS would be an optimized target disorder of Korean medicine. This study aims to present the recent information especially in aspect of medical policy and new diagnosis criteria for CFS. Methods: The literature survey was conducted using the terms of "chronic fatigue syndrome", "myalgic encephalomyelitis" and "fibromyalgia" in PubMed database and Google database in its entirety from January 2011 to February 2019. The in-depth review was made focusing on the changes in policy and medical perspective for CFS. Results: Recently large medical attentions and researches for CFS have been existed worldwide. By supporting of USA government, IOM made a report which leaded to a turning point in clinical practices and research in 2015. This report recommended a new name of CFS to systemic exertion intolerance disease (SEID), and new diagnostic criteria focusing on post-exertional malaise, unrefreshing sleep, cognitive impairment and orthostatic intolerance. The medical perspective also was changed into "a serious, chronic, complex, systemic disease" from a psychological-like disorder, and then UAS and EU governments sharply increased the research grants. Conclusions: This study provided practitioners in Korean medicine (KM) a core information about the recent changes in CFS-related perspectives. This review would be helpful for KM-derived researches or therapeutics development for CFS.

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“…Studies have shown that chronic fatigue was most common among women and caucasians and signi cantly related to depression, mixed anxiety and depressive disorder, and generalized anxiety disorder [9] .The etiology and pathogenesis of fatigue are largely unknown. In recent years, researchers have been exploring various therapeutic measures such as acupuncture and moxibustion [10],spa therapy [11] and chinese herbal medicine [12] .There is still a lacking of objective and effective comprehensive evaluation methods for the diagnosis of fatigue, which leads to the inability to carry out targeted interventions when fatigue occurs in the early stage of disease. Hence it is imperative to establish a comprehensive objective evaluation method for fatigue.…”

Section: Introductionmentioning

confidence: 99%

Clinical data mining on network of symptom and index and correlation of tongue-pulse data in fatigue population

Shi

Cui

et al. 2020

Preprint

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BackgroundFatigue is a kind of non-specific symptom, which is widely found in sub-health and various diseases. It is closely related to people's physical and mental health.Due to lack of objective evidence, it is often neglected in clinical diagnosis,especially in the early stage of disease.A large number of clinical practices and studies have shown that tongue and pulse image are reflection of overall state of the body.Establishing an objective evaluation method for diagnosis of disease fatigue and non-disease fatigue by combining clinical symptom and index and tongue and pulse data is of great significance for timely and effective clinical treatment.MethodsIn this study, 2362 physical examination subjects were divided into healthy control, the group of sub-health fatigue and disease fatigue ,used complex network technology to screen out the core symptoms and western medicine indexes of fatigue,respectively. Constructed the core symptom network and the core symptom-index network. At the same time, used canonical correlation analysis to get the associated relationship of tongue and pulse, and analyzed the characteristic of the tongue and pulse data.ResultsThere were some similarities between the core symptoms of sub-health fatigue and disease fatigue,as well as differences. Symptom-index associated analysis of disease fatigue showed that the core indexes in the group of disease fatigue group had a significant canonical correlation, with the canonical correlation coefficient was 0.42 (P < 0.05). There was no statistically significant correlation between the tongue and pulse data in sub-health fatigue group.ConclusionsThe complex network technology was suitable for the correlation analysis of symptoms and indexes in the fatigue population, and the tongue and pulse objective data had certain diagnostic contribution to the classification of fatigue population.Name of the registry: Chinese Clinical Trial RegistryTrial registration number: ChiCTR-IOR-15006502; ChiCTR1900026008Date of registration: Jun. 04th, 2015URL of trial registry record:http://www.chictr.org.cn/showprojen.aspx?proj=11119;http://www.chictr.org.cn/edit.aspx?pid=38828&htm=4 (This is a retrospective registration)

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Yang/Qi Invigoration: An Herbal Therapy for Chronic Fatigue Syndrome with Yang Deficiency?

Cited by 49 publications

References 45 publications

Association of Menopausal Symptoms with Different Constitutions in Climacteric Women

Association of Menopausal Symptoms with Different Constitutions in Climacteric Women

Minireview for Chronic Fatigue Syndrome and its Medical Attention recently

Clinical data mining on network of symptom and index and correlation of tongue-pulse data in fatigue population

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