DOI: 10.7717/peerj.5/fig-5
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Abstract: ABSTRACTFragments of prostatic acid phosphatase ) in human semen dramatically increase HIV infection efficiency by increasing virus adhesion to target cells. PAP 248−286 only enhances HIV infection in the form of amyloid aggregates termed SEVI (Semen Enhancer of Viral Infection), however monomeric PAP 248−286 aggregates very slowly in isolation. It has therefore been suggested that SEVI fiber formation in vivo may be promoted by exogenous factors. We show here that a bacterially-produced extracellular amyloi…

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