XCI.—The constituents of Gloriosa superba

Clewer, Hubert William Bentley; Green, Stanley Joseph; Tutin, Frank

doi:10.1039/ct9150700835

Cited by 40 publications

(9 citation statements)

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“…The roots and tubers of this plant have been used in traditional Indian medicine for the treatment of gout, rheumatic arthritis, diseases of the skin and liver, and several other purposes (Finnie and Staden, 1994). Since the detection of colchicine in Gloriosa (Clewer et al, 1915), a number of researchers have suggested that Gloriosa could serve as a commercial source of colchicine (Sarin et al, 1977;Srivastava and Chandra, 1977), as the colchicine content in the genera Colchicum has been reported to be lower than in Gloriosa (Bellet and Graignault, 1985). Colchicine, the main alkaloid of Gloriosa superba, was a useful agent in the treatment of acute attacks of gout (Robert et al, 1987) cirrhosis of the liver (Kershowtrich et al, 1988) and familial Mediterranean fever (Goldfinger et al 1972).…”

Section: Introductionmentioning

confidence: 99%

Improved Growth And Colchicine Concentration In <i>Gloriosa Superba</i> On Mycorrhizal Inoculation Supplemented With Phosphorus-Fertilizer

Pandey¹,

Malik²,

Dey³

et al. 2014

Afr. J. Trad. Compl. Alt. Med.

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Background: Gloriosa superba produces an array of alkaloids including colchicine, a compound of interest in the treatment of various diseases. The tuber of Gloriosa superba is a rich source of colchicine which has shown anti-gout, anti-inflammatory, and anti-tumor activity. However, this promising compound remains expensive and Gloriosa superba is such a good source in global scale. Increase in yield of naturally occurring colchicine is an important area of investigation. Materials and Methods:The effects of inoculation by four arbuscular mycorrhizal (AM), fungi, Glomus mossae, Glomus fasciculatum, Gigaspora margarita and Gigaspora gilmorei either alone or supplemented with P-fertilizer, on colchicine concentration in Gloriosa superba were studied. The concentration of colchicine was determined by high-performance thin layer chromatography. Results: The four fungi significantly increased concentration of colchicine in the herb. Although there was significant increase in concentration of colchicine in non-mycorrhizal P-fertilized plants as compared to control, the extent of the increase was less compared to mycorrhizal plants grown with or without P-fertilization. This suggests that the increase in colchicine concentration may not be entirely attributed to enhanced P-nutrition and improved growth. Among the four AM fungi Glomus mossae was found to be best. The total colchicine content of plant (mg / plant) was significantly high in plants inoculated with Glomus mossae and 25 mg kg -1 phosphorus fertilizer (348.9 mg /plant) while the control contain least colchicine (177.87 mg / plant).

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Section: Introductionmentioning

confidence: 99%

Improved Growth And Colchicine Concentration In <i>Gloriosa Superba</i> On Mycorrhizal Inoculation Supplemented With Phosphorus-Fertilizer

Pandey¹,

Malik²,

Dey³

et al. 2014

Afr. J. Trad. Compl. Alt. Med.

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“…In traditional Indian medicine, roots and tubers of G. superba have been used for the treatment of gout, rheumatic arthritis, diseases of skin and liver, and several other purposes (Finnie and Van Staden 1994 ) . Several researchers have suggested that Gloriosa could serve as a commercial source of colchicine (Sarin et al 1977 ;Srivastava and Chandra 1977 ) , since the detection of colchicine in Gloriosa (Clewer et al 1915 ) as the colchicine content in the genera Colchicum has been reported to be lower than in Gloriosa (Bellet and Gaignault 1985 ) . Although attempts have been made by several workers for in vitro studies and biosynthesis of secondary metabolites from this highly valuable endangered medicinal plant species (Ghosh et al 2002(Ghosh et al , 2006Hassan and Roy 2005 ;Krishnamurthy 2000 , 2002 ), considerable efforts are still required to make it more economical and practical.…”

Section: Gloriosa Superba Lmentioning

confidence: 97%

In Vitro Protocols for Ornamental Climbers

Shaheen

Shahzad

2015

Biotechnological Strategies for the Conservation of Medicinal and Ornamental Climbers

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Since the time immemorial, plants and plant parts thereof have been used as medicinal sources to cure various ailments and diseases. Recent era witnessed a great loss of this natural wealth because of its excessive use and overexploitation. Thus, it is the need of an hour to take immediate and possible measures for conserving such a great wealth. With the advent of biotechnological approaches, new vitas and horizons were broadened in every sphere of research including plant biotechnology that boosted during the present century and played a vital role in conserving ornamental plants, thus maintaining the depleting natural wealth under laboratory conditions in a short span of time. In vitro studies of several important ornamental climbers have been carried out by different workers, viz., Gloriosa superba , Ceropegia spp . , Allamanda , Passifl ora spp., etc. The present chapter deals with the detailed account of successful protocols developed through in vitro propagation of such elite germplasms.

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“…This artifi cial chromosome doubling attracted many researchers to design studies/ experiments in order to test different methodologies/protocols to induce chromosome doubling in agricultural crops using cold treatments, heat shocks, and antimitotic agents. The discovery of colchicine from Gloriosa by Clewer et al ( 1915 ) perfected its use in chromosome doubling and with the passage of time, it became a method of choice for artifi cial chromosome doubling (Blakeslee 1939 ) in at least 48 agricultural crops. Regardless of its extensive exploitation, effectiveness, and application in agricultural crops, there are numerous disadvantages associated with its usage that include occurrence of mixed polyploids (Pei 1985 ), loss of sterility, decrease in fertility, abnormal growth, chromosomes rearrangements, and gene mutations (Luckett 1989 ).…”

Section: Increase In Ploidy Levelmentioning

confidence: 99%

Androgenesis: A Fascinating Doubled Haploid Production Process

Asif

2013

Progress and Opportunities of Doubled Haploid Production

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XCI.—The constituents of Gloriosa superba

Cited by 40 publications

References 0 publications

Improved Growth And Colchicine Concentration In <i>Gloriosa Superba</i> On Mycorrhizal Inoculation Supplemented With Phosphorus-Fertilizer

Improved Growth And Colchicine Concentration In <i>Gloriosa Superba</i> On Mycorrhizal Inoculation Supplemented With Phosphorus-Fertilizer

In Vitro Protocols for Ornamental Climbers

Androgenesis: A Fascinating Doubled Haploid Production Process

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