Metallic silver, silver nanoparticles (AgNp) and nanocomposites based on silver are widely used in medicine, due to their antibacterial and antiseptic properties. The main goals of the present work were: (1) research of various types of liquids containing AgNp (including AgNp produced by biosynthesis technology using dessert plants (nopal, agave) extracts to reduce the silver); (2) research of sedimentation from liquids of AgNp on the surface of Hydroxyapatite (HA) implant coatings deposited by plasma spraying; (2) preliminary evaluation of antibacterial properties of HA coating modified with AgNp. The first test shows significant antibacterial activity of HA coatings containing AgNp produced by biosynthesis technology.