volume 61, issue 3, P263-265 2005
DOI: 10.1107/s1744309105004823
View full text
|
Sign up to set email alerts
|
Share

Abstract: The crystal structure of the 26 kDa glutathione S‐transferase from Schistosoma japonicum (SjGST) was determined at 3 Å resolution in the new space group P212121. The structure of orthorhombic SjGST reveals unique features of the ligand‐binding site and dimer interface when compared with previously reported structures. SjGST is recognized as the major detoxification enzyme of S. japonicum, a pathogenic helminth causing schistosomiasis. As resistance against the established inhibitor of SjGST, praziquantel, has …

Expand abstract

Search citation statements

Order By: Relevance

Citation Types

0
10
0

Paper Sections

0
0
0
0
0

Publication Types

0
0
0
0

Relationship

0
0

Authors

Journals