2017
DOI: 10.1016/s2352-3026(17)30052-2
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Abstract: SummaryBackgroundGlobal inequalities in access to health care are reflected in differences in cancer survival. The CONCORD programme was designed to assess worldwide differences and trends in population-based cancer survival. In this population-based study, we aimed to estimate survival inequalities globally for several subtypes of childhood leukaemia.MethodsCancer registries participating in CONCORD were asked to submit tumour registrations for all children aged 0–14 years who were diagnosed with leukaemia be… Show more

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Cited by 143 publications
(110 citation statements)
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References 28 publications
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“…The patterns of survival by age at diagnosis are consistent with other data from the United States and other countries . The survival of infants diagnosed with ALL is markedly lower than that for any other age group, which reflects the higher proportion in this age group of children diagnosed with ALL whose profile shows mixed‐lineage leukemia gene rearrangements .…”
Section: Discussionsupporting
confidence: 85%
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“…The patterns of survival by age at diagnosis are consistent with other data from the United States and other countries . The survival of infants diagnosed with ALL is markedly lower than that for any other age group, which reflects the higher proportion in this age group of children diagnosed with ALL whose profile shows mixed‐lineage leukemia gene rearrangements .…”
Section: Discussionsupporting
confidence: 85%
“…Biologic features of childhood leukemia that vary by age and have prognostic implications, such as the DNA index and specific chromosomal rearrangements, may explain differences in survival by age group. The current finding that survival differences in race were most pronounced at age <1 year or >4 years needs further study . We also observed that, as previously reported, boys have lower survival from ALL than girls.…”
Section: Discussionsupporting
confidence: 79%
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“…ALL is the commonest childhood malignancy and the 5-year event-free survival (EFS) is now approaching 90% in developed countries. [5][6][7] However, the survival outcome is still suboptimal in developing countries. 8,9 A recent multicenter study from China reported 5-year EFS of 79.9%.…”
Section: Discussionmentioning
confidence: 99%
“…AML develops through a multistep process of genomic and epigenetic alterations which results in disease progression . Dismal survival and poor outcomes in this disease result in a large unmet need to discover newer biomarkers and potential therapeutic targets …”
Section: Introductionmentioning
confidence: 99%