Woman With New-Onset Boggy Scalp

Lipedematous alopecia: An unusual sequela of discoid lupus, or other co-conspirators at work?

“…4 Microscopic features in lipedematous alopecia include a thickened subcutaneous layer, mild hyperkeratosis, and a perivascular lymphocytic infiltrate. [2][3][4][5][6][7][8] Follicular plugging has been noted in two cases, 2,5 and follicular fibrosis and mucin deposition in another case, 4 changes seen in discoid lupus and in our own case. In patient 1, a biopsy specimen from 5 years earlier demonstrated features of discoid lupus erythematosus (DLE).…”

“…In all, 11 additional cases of lipedematous alopecia, including our own, have been detailed, with 7 cases occurring in African American women. [3][4][5][6][7][8][9] Other clinical characteristics include later onset (mean age 52 years), a female predominance, and frequent involvement of the scalp vertex (Table I). Scalp thickness in affected patients has ranged from 9 to 15 mm.…”

“…Scalp thickness in affected patients has ranged from 9 to 15 mm. [2][3][4][5][6][7][8][9] The normal thickness of the human scalp is 5 to 6 mm. 10 …”

Lipedematous scalp and lipedematous alopecia: A clinical and histologic analysis of 3 cases

“…S calp thicknening caused by an abnormally increased subcutaneous layer not attributed to tumors is a rare condition of unknown origin that has been reported under the terms of lipedematous alopecia [1][2][3][4][5][6][7] if it is associated with hair growth abnormalities, or lipedematous scalp 8,9 if no hair abnormalities are present. Some authors speculate that they represent two distinct entities or two stages along the spectrum of a single scalp disorder.…”

A Case of Lipedematous Alopecia Occurring in a Male Patient

“…Lipedematous alopecia was initially reported in 1961, and so far 4 female cases have been reported in the literature [1][2][3]. This rare disease is characterized by diffuse alopecia due to the thickening of the layer of adipose tissue covering the scalp.…”