“…Nine of the 12 genes remained significantly up-regulated until Day 14 after bleomycin administration (C6, Cthrc1, Fhl2, Gal, Grem1, Lcn2, Mmp7, Pcsk1, and Slc2a5). Interestingly, we identified a number of molecules that were associated directly or indirectly with Wnt/b-catenin signaling, including Mmp7, Fhl2, Cthrc1, and Grem1, thus emphasizing the potential significance of this pathway in IPF (52)(53)(54)(55)(56)(57).…”