2020
DOI: 10.1016/j.jcpx.2020.100050
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Timo Koch,
Martin Schneider,
Rainer Helmig
et al.

Abstract: We present a new method for modeling tissue perfusion on the capillary scale. The microvasculature is represented by a network of one-dimensional vessel segments embedded in the extra-vascular space. Vascular and extra-vascular space exchange fluid over the vessel walls. This exchange is modeled by distributed sources using smooth kernel functions for the extra-vascular domain. It is shown that the proposed method may significantly improve the approximation of the exchange flux, in comparison with existing me…

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