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“…The classical definition of Cry as a regulator of circadian rhythms can now be expanded to the biology of glial cells, GB progression and the expansion of lifespan in Drosophila. This plethora of different phenotypes associated with one gene is now a common feature previously described for Troponin I [47][48][49], Caspases [50][51][52] or even other circadian genes as per1 [53,54] and contributes to the explanation of the multiple phenotypes observed in patients.…”
Section: Discussionsupporting
confidence: 54%
“…The classical definition of Cry as a regulator of circadian rhythms can now be expanded to the biology of glial cells, GB progression and the expansion of lifespan in Drosophila. This plethora of different phenotypes associated with one gene is now a common feature previously described for Troponin I [47][48][49], Caspases [50][51][52] or even other circadian genes as per1 [53,54] and contributes to the explanation of the multiple phenotypes observed in patients.…”
Section: Discussionsupporting
confidence: 54%