volume 29, issue 4, P903-911 2012
DOI: 10.3233/jad-2012-111784
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Sarah Benisty, Sonia Reyes, Ophelia Godin, Dominique Hervé, Nikola Zieren, Eric Jouvent, Yicheng Zhu, Marco During, Martin Dichgans, Hugues Chabriat

Abstract: To better characterize the clinical spectrum related to white-matter hyperintensities (WMH) in small vessel disease, 66 patients with WMH but without any lacunar infarct were selected out of a cohort of 248 CADASIL individuals. Characteristics of these patients were compared to those of patients with lacunar infarcts. Relationships between the normalized volume of WMH (nWMH), presence of microhemorrhages, brain parenchymal fraction (BPF). and cognitive performances were assessed. The Trail Making Test (TMT) A …

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