Where does the toxicity of metal oxide nanoparticles come from: The nanoparticles, the ions, or a combination of both?

Wang, Dali; Zhao, Lin; Wang, Ting; Yao, Zhifeng; Qin, Mengnan; Zheng, Shourong; Lu, Wei

doi:10.1016/j.jhazmat.2016.01.066

Cited by 284 publications

(151 citation statements)

References 35 publications

Supporting

Mentioning

131

Contrasting

Unclassified

Order By: Relevance

“…This results are in accordance with the finding that the higher the ionic potential, the greater the degree of the ion-ion screening effects in an oxide by surrounding anions (Erdemir et al, 2005). Several studies have confirmed that the released metal ions in culture media from some nanomaterials were the proximal cause of adverse effects (Alaraby et al, 2016;Wang et al, 2014;Wang et al, 2016). Another parameter, Z/r, represents electro negativity or propensity of metal ions to bind to bioligands.…”

Section: Discussionsupporting

confidence: 89%

Predicting toxic potencies of metal oxide nanoparticles by means of nano-QSARs

Zhao

et al. 2016

Nanotoxicology

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 89%

Predicting toxic potencies of metal oxide nanoparticles by means of nano-QSARs

Zhao

et al. 2016

Nanotoxicology

View full text Add to dashboard Cite

show abstract

“…Literature data showed that Zn 2+ ions released from ZnO nanoparticles are related to their cytotoxic potential (Wang et al, 2014;Wang et al, 2016). To verify if the toxicity of metal nanoparticles is due to the same nanoparticles or ions, we included the effect of a zinc salt on the cell viability and compared this with ZnO nanoparticles.…”

Section: Discussionmentioning

confidence: 99%

ZnO nanoparticle tracking from uptake to genotoxic damage in human colon carcinoma cells

Condello

Berardis²,

Ammendolia³

et al. 2016

Toxicology in Vitro

View full text Add to dashboard Cite

“…The lack of antimicrobial activity of the Fe 2 O 3 NPs could be associated with the low solubility and the free ions in the media (Arakha et al, 2015;Wang et al, 2016). Furthermore, the aggregation of the Fe 2 O 3 NPs in the media due to the antimicrobial effects is related to their nano-scale interactions (Ismail, Sulaiman, Abdulrahman, & Marzoog, 2015;Sharaf, Abbas, & Ismaeil, 2019).…”

Section: Discussionmentioning

confidence: 99%

In vitro antimicrobial effect of metallic nanoparticles on phytopathogenic strains of crop plants

Vera‐Reyes

Esparza‐Arredondo²,

Lira-Saldívar³

et al. 2019

Journal of Phytopathology

View full text Add to dashboard Cite

In this research, the in vitro antimicrobial effect of zinc oxide (ZnO), copper oxide (CuO) and iron oxide (Fe2O3) nanoparticles (NPs)—with average sizes of 20, 46 and 30 nm, respectively—on the root rot disease caused by the fungus Fusarium oxysporum and on blight disease caused by the fungus Alternaria solani were studied. Also, bacterial diseases caused by Clavibacter michiganensis and Pseudomonas syringae that infects a wide range of plant species were assessed. Different concentrations of NPs (0, 100, 250, 500, 700 and 1,000 mg/L) were prepared on PDA agar or King's B medium in a complete randomized design with four replicates. According to the results, ZnO NPs exhibited an outstanding inhibitory effect against fungi and bacteria strains. The above results were associated with the smaller particle size. Fungi strains showed a differential sensitivity depending on the kind of NPs used. A. solani showed the highest sensitivity to ZnO NPs at 1,000 mg/L (99%), followed by CuO NPs at the same dose (95%). Fe2O3 NPs at all evaluated doses had no inhibitory effects on the mycelia growth of this strain, although F. oxysporum revealed greater effectiveness of the CuO NPs (96%) compared with ZnO NPs since it only inhibited 91% of the mycelial growth. The antibacterial activity was studied through optical density. C. michiganensis was found to be more sensitive to ZnO NPs because a lesser dose (700 mg/L) was required to reduce the bacterial growth (90%); in comparison, P. syringae required a dose of 1,000 mg/L to inhibit its growth (67%). CuO NPs displayed the smallest growth inhibition against the bacteria strains analysed. The antimicrobial effect of the metallic NPs that were assayed increased with higher doses.

show abstract

Where does the toxicity of metal oxide nanoparticles come from: The nanoparticles, the ions, or a combination of both?

Cited by 284 publications

References 35 publications

Predicting toxic potencies of metal oxide nanoparticles by means of nano-QSARs

Predicting toxic potencies of metal oxide nanoparticles by means of nano-QSARs

ZnO nanoparticle tracking from uptake to genotoxic damage in human colon carcinoma cells

In vitro antimicrobial effect of metallic nanoparticles on phytopathogenic strains of crop plants

Contact Info

Product

Resources

About