What to eat for a better sleep in haemodialysis patients: Potential role of B vitamins intake and appetite

Abstract

Objective:Sleeping disorders are common among Haemodialysis-HD patients. In addition to well-known factors, food consumption impact on sleep quality needs being discovered. Aim was to examine the nutrition-related factors that may influence sleep quality in HD patients.Methods:One hundred and three patients in three HD centres participated. Data were collected with Pittsburgh Sleep Quality Index-PSQI and Questionnaire Form about socio-demographic characteristics and appetite. Biochemical findings were obtained; food consumption for three consecutive days was recorded. Independent Samples t/Mann Whitney U tests for mean comparison; Logistic Regression Analysis for determining variables affecting sleep quality, were used.Results:Mean age was 59.19±14.57 years. 51.5% were women. 37.9% had good (PSQI<5) and 62.1% had poor (PSQI≥5) sleep quality. Appetite had significant impact on sleep quality; poor sleeping risk was 4.194 fold higher in patients with bad appetite than those with good appetite (p=0.038). Biochemical findings of poor and good sleepers were similar, except for potassium and creatinine. Vitamins B1, B6 and folate intake of good and poor sleepers were significantly different. Patients with good sleep quality consumed significantly higher amounts of above B vitamins (p=0.030, p=0.036, p=0.034, respectively).Conclusions:Favourable effect of appetite and certain nutrients intake on sleep quality in HD patients was shown. Improving nutritional status of HD patients has potential to increase their sleep quality.

The injection of maternal B complex vitamin during the transition period: The impact on performance, thyroid hormones levels and immunological parameters in the Sannen goats and their kids, as well as the faeces status of newborn kids

“…As B vitamins are enzymatic cofactors or metabolic constituents, they are essential to metabolic processes such as Kreb's cycle, gluconeogenesis, as well as metabolism of carbohydrate, fatty and protein (Al‐Abbasy, 2013 ; McDowell, 2000 ; Zimmerly & Weiss, 2001 ). In this study, by increasing appetite (Ongan & Yuksel, 2017 ) and reducing oxidative stress (Dalto & Matte, 2017 ) in the transition period, B vitamin injection led to a reduction in energy‐negative balance by improving animal feed intake. Accordingly, the increase in feed intake and nutrient digestibility in the B complex vitamin group was responsible for improving body weight in goats and their offspring.…”

“…Further, the rapid growth of the uterus and fetus during pregnancy, coupled with lactation, results in a rise in nutrient intake during the transition period (NRC, 2012 ). Research shows that B vitamin helps maintain normal appetites (Ongan & Yuksel, 2017 ) and animal performance (Ren et al., 2022 ). In addition to their role as cofactors in thyroid hormone synthesis (Habeeb & Gad, 2019 ), they also play a significant role in immunity (Hosomi & Kunisawa, 2017 ; Suzuki & Kunisawa, 2015 ).…”

Sleep disorders related to nutrition and digestive diseases: a neglected clinical condition

“…Nutrients favoring or inhibiting their release influence the quality of sleep, whereas foods acting on tryptophan availability or the synthesis of serotonin and melatonin promote sleep 20 . Some vitamins (B1 and B6) also induce production and release of melatonin and serotonin 21 , 22 .…”

Mitochondrial DNA Mutation, Diseases, and Nutrient-Regulated Mitophagy

“…A wide variety of B vitamins influences nuclear transcription and ER metabolite activity, and, ultimately, these effects are concentrated on mitochondrial function (33). B vitamin deficiency has many consequences, including appetite loss and uncharacteristic emotional sensitivity, and, ultimately, pathological changes in the nervous system (114). Vitamins C and D are also important for mitochondrial function.…”