Infectious Disease Clinics of North America volume 27, issue 1, P133-147 2013 DOI: 10.1016/j.idc.2012.11.014 View full text
Oriol Sibila, Marcos I. Restrepo, Antonio Anzueto

Abstract: Community-acquired pneumonia (CAP) is the leading cause of death from infectious diseases in the United States. The mortality rate due to severe CAP has shown little improvement over the past few years, with a rate as high as 50% mainly in patients admitted to intensive care units. Death and adverse outcomes from CAP result from a complex interplay between the pathogen and the host. Several therapies have been tested in patients with severe CAP in recent years. This article reviews recent data regarding differ…

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