What is Schonlein-Henoch purpura, and why should we care?

Piette, Warren W.

doi:10.1001/archderm.133.4.515

Cited by 8 publications

(2 citation statements)

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“…It is the most common connective tissue disorder in children, usually seen 1-3 weeks after an upper respiratory tract infection or drug ingestion. Characteristic signs of the disease are a purpuric rash, arthralgia, abdominal pain with vomiting, gastrointestinal bleeding and renal dysfunction Piette 1997). The skin lesions consist of palpable purpura, sometimes necrotising, on the legs and, rarely, on the trunk, which might be a predictive factor for renal involvement (Tancrede-Bohin et al 1997).…”

Section: Introductionmentioning

confidence: 99%

Henoch–Schonlein purpura in pregnancy

Kalmantis

Iavazzo

Vranos

et al. 2008

Journal of Obstetrics and Gynaecology

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Henoch-Schonlein purpura (HSP) is a hypersensitivity vasculitis. This is a case report of HSP during pregnancy and a review of the literature in this rare pregnant disease. We present a case of a 32-year-old woman with HSP. Treatment with low-dose oral corticosteroids was administered leading to a beneficial outcome for the fetus and the mother. Henoch-Schonlein purpura is the most common connective tissue disorder of children. It is rarely reported in adults. Only 16 cases of HSP during pregnancy have been described in the literature worldwide, and this is the 17th reported case.

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Section: Introductionmentioning

confidence: 99%

Henoch–Schonlein purpura in pregnancy

Kalmantis

Iavazzo

Vranos

et al. 2008

Journal of Obstetrics and Gynaecology

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“…Bei den betroffenen Kindern sind oft IgA1 oder polymeres IgA im Serum erhöht. Bei der begleitenden Nephropathie fand man mesangiale Ablagerungen von abnorm O-glykolisiertem IgA1 [34]. Oft geht der PSH eine Infektion der oberen Atemwege voraus.…”

Section: Purpura Schönlein-henoch Im Kindes-und Jugendalterunclassified

Leukozytoklastische Vaskulitis

2004

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Leukocytoclastic vasculitis (LcV) is the most common form of cutaneous vasculitis. Often LcV results from deposition of immune complexes in the vascular wall. When IgA is the dominant immunoglobulin in these complexes, systemic involvement is likely (Henoch-Schönlein purpura), being more severe in adults. LcV in which immune complexes are composed of IgG or IgM are more often limited to the skin and may additionally show minor systemic involvement. In other forms of LcV additional pathophysiological factors play a role. LcV can also be a presenting or accompanying symptom of severe systemic ANCA-associated vasculitis. In some cases, LcV is a sign of bacteriemia. The aim of diagnostic procedures is to determine the specific type of vasculitis and degree of systemic involvement as well as possible causes. If no trigger or cause can be found, uncomplicated cases of LcV should be treated symptomatically. Corticosteroids are indicated at initial signs of necrosis or ulceration. Chronic recurrent LcV may respond to dapsone or colchicine. Severe systemic vasculitis requires immunosuppressive therapy.

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Vaskulitiden, Vaskulopathien, Pannikulitiden

Sunderkötter

Bonsmann

Roth

Pädiatrische Dermatologie

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What is Schonlein-Henoch purpura, and why should we care?

Cited by 8 publications

References 0 publications

Henoch–Schonlein purpura in pregnancy

Henoch–Schonlein purpura in pregnancy

Leukozytoklastische Vaskulitis

Vaskulitiden, Vaskulopathien, Pannikulitiden

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