What every dermatologist should know about homeopathy

Burgdorf, Walter H. C.; Happle, Rudolf

doi:10.1001/archderm.132.8.955

Cited by 10 publications

(2 citation statements)

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“…Despite the acknowledgement of the existence of hormesis, its importance has been disregarded by the scientific community, with one of the reasons being the close association of the concept of hormesis with the highly controversial medical practice of homeopathy (Burgdorf and Happle 1996;Clement 1997;Cook and Calabrese 2006). Calabrese and Blain (2005) developed a hormesis database, containing 5600 hormetic-like dose response relationships over approximately 900 agents from a broadly diversified spectrum of chemical classes and physical agents, stressing the general robustness of published studies to establish support for the hormetic doseresponse hypothesis.…”

Section: Discussionmentioning

confidence: 99%

Hormesis [Biological Effects of Low Level Exposures (Belle)] and Dermatology

Thong¹,

Maibach²

2008

Dose-Response

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ᮀ Hormesis, or biological effects of low level exposures (BELLE), is characterized by nonmonotonic dose response which is biphasic, displaying opposite effects at low and high dose. Its occurrence has been documented across a broad range of biological models and diverse type of exposure. Since hormesis appears to be a relatively common phenomenon in many areas, the objective of this review is to explore its occurrence related to dermatology and its public health and risk assessment implication. Hormesis appears to be a common phenomenon in in-vitro skin biology. However, in vivo data are lacking and the clinical relevance of hormesis has yet to be determined. Better understanding of this phenomenon will likely lead to different strategies for risk assessment process employed in the fields of dermatologic toxicology and pharmacology. We believe that hormesis is a common phenomenon and should be given detailed consideration to its concept and its risk assessment implications, and how these may be incorporated into the experimental and regulatory processes in dermatology. The skin, with its unique characteristics, its accessibility, and the availability of non-invasive bioengineering and DNA microarray technology, will be a good candidate to extend the biology of hormesis.

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Section: Discussionmentioning

confidence: 99%

Hormesis [Biological Effects of Low Level Exposures (Belle)] and Dermatology

Thong¹,

Maibach²

2008

Dose-Response

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“…This is consistent with other surveys. Recent surveys in developing countries have demonstrated that the use of alternative therapeutic regimes has an enormous presence in the healthcare system, because the patients from all socio-demographic groups are becoming disappointed in, and frustrated by, the increasing impersonal, technical nature of procedures of standard medicine [41][42][43][44][45][46]. 3.…”

Section: Use Of Traditional Medicine In Eritreamentioning

confidence: 99%