What does the nose know? Olfactory function predicts social network size in human

Zou, Lai‐quan; Yang, Zhuo-ya; Wang, Yi; Lui, Simon S.Y.; Chen, An-tao; Cheung, Eric F.C.; Chan, Raymond C.K.

doi:10.1038/srep25026

Cited by 47 publications

(42 citation statements)

References 44 publications

(47 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These findings extend the results recently published by Zou and colleagues12. The current data are consistent with the large body of evidence that social interactions are intimately linked to health status (20–25), and includes olfactory identification performance as another key aspect of health.…”

Section: Discussionsupporting

confidence: 93%

“…Older adults are the fastest growing division of the population, and a large proportion of those will experience age-related chemosensory loss1317, and older people generally have smaller social networks and are often socially more isolated. In line with the results of Zou et al 12,. we hypothesized that smaller social lives would be manifested in individuals exhibiting reduced ability to identify odors and that these associations would be more pronounced in women.…”

supporting

confidence: 92%

“…Given the relatively low sample size (n = 31) employed by Zou and colleagues12, our different results could be explained by our large sample providing achieved explanatory power, pw > 0.99.…”

Section: Discussionmentioning

confidence: 72%

“…Zou and colleagues12 did not report a significant result for olfactory identification, although they did for olfactory sensitivity. Given the relatively low sample size (n = 31) employed by Zou and colleagues12, our different results could be explained by our large sample providing achieved explanatory power, pw > 0.99.…”

Section: Discussionmentioning

confidence: 89%

“…In a small homogenous sample of young adult ethnic Chinese, Zou and colleagues12 demonstrated a positive correlation between the number of an individual’s social contacts and their olfactory sensitivity as well as with functional connectivity between amygdala and the orbitofrontal cortex. However, they did not find an association with the ability to identify odor, in which there are well-established sex differences.…”

mentioning

confidence: 99%

See 4 more Smart Citations

Olfactory function and the social lives of older adults: a matter of sex

Boesveldt

Yee

McClintock

et al. 2017

Sci Rep

View full text Add to dashboard Cite

Social factors play a critical role in a panoply of health processes, including, as recently demonstrated, olfaction. Here, we investigated sex-dependent differences in the relationship between social lives and ability to identify odors in a large sample of nationally representative older US adults (n = 3005, National Social Life and Aging Project (NSHAP)). Social life was measured by the number of friends and close relatives as well as frequency of socializing. We here confirm the association between social lives and olfactory function and extend the notion by showing specifically that olfactory identification ability is modulated by sex in older adults. The connection between olfactory performance and social lives could reflect social modulation of aging as has been reported for health in general. Future studies are necessary to elucidate the precise mechanisms underlying this association and sex difference.

show abstract

Section: Discussionsupporting

confidence: 93%

supporting

confidence: 92%

Section: Discussionmentioning

confidence: 72%

Section: Discussionmentioning

confidence: 89%

mentioning

confidence: 99%

See 3 more Smart Citations

Olfactory function and the social lives of older adults: a matter of sex

Boesveldt

Yee

McClintock

et al. 2017

Sci Rep

View full text Add to dashboard Cite

show abstract

Otolaryngic sensory loss as a measure of frailty among older US adults

Hura

Bernstein

Mady

et al. 2021

Int Forum Allergy Rhinol

View full text Add to dashboard Cite

Background Frailty is a syndrome characterized by reduced physiologic reserve and increased vulnerability to poor health outcomes. Disruption of sensorineural function appears to serve as a novel biomarker of frailty. Using population‐level data, we sought to characterize the association between otolaryngic sensory dysfunction and frailty. Methods A cross‐sectional analysis of the 2011‐2012 US National Health and Nutrition Examination Survey was performed on adults ≥40 years of age (n = 2138). Participants were grouped by subjective gustatory dysfunction (sGD), olfactory dysfunction (sOD), hearing loss (sHL), and measured hearing loss (mHL) with pure tone averages (PTAs). Frailty was operationalized using a continuous 36‐item frailty index (FI) scored from 0 to 1, stratified in 4 categories (“non‐frail,” “vulnerable,” “frail,” or “most frail”). Results All sensory loss groups had significantly higher FI scores than those without sensory loss (sGD = 0.15; sOD = 0.14; sHL = 0.15; low‐frequency mHL = 0.16; high‐frequency mHL = 0.14 vs control = 0.11; p < 0.007 for all). “Vulnerable” individuals had increased odds of sOD (adjusted odds ratio [aOR], 1.45; 95% confidence interval [CI], 1.05‐2.00), whereas “frail” individuals had increased odds of sOD (aOR, 1.85; 95% CI, 1.26‐2.71) and low‐frequency mHL (aOR, 4.01; 95% CI, 1.27‐12.63). The “most frail” individuals had increased odds of sHL (aOR, 11.72; 95% CI, 2.88‐47.66) and high‐frequency mHL (aOR 5.10; 95% CI, 1.72‐15.12). PTAs were linearly associated with FI (low: β = 10.15; 95% CI, 1.78‐18.51; high: β = 19.85; 95% CI, 5.19‐34.53). Conclusion Otolaryngic sensory loss is associated with increased frailty. Independent association of frailty with measures of olfaction and hearing suggests that olfactory and hearing assessments may help identify at‐risk individuals with modifiable risk factors.

show abstract

Self‐powered virtual olfactory generation system based on bionic fibrous membrane and electrostatic field accelerated evaporation

Yang

Shi

Tao

et al. 2022

EcoMat

View full text Add to dashboard Cite

Olfactory plays an important role in virtual reality technology. In this work, a bionic fibrous membrane (BFM) integrated with the function of electrostatic field accelerated evaporation (EFAE) is applied for realizing the virtual olfactory generation (VOG) system. The BFM is capable of self‐driven unidirectional liquid transmission and EFAE process is induced on BFM by using an ultrafast voltage‐elevation triboelectric nanogenerator (UVE‐TENG). The output voltage from UVE‐TENG can reach 8 kV within 40 ms, which is enough to maintain all of the functions of VOG system. Meanwhile, the output current from UVE‐TENG is smaller than 1 μA, leading to a safe and human compatible system. The flow rate of the volatile liquid spray from the system emitter can reach 0.1 μl/s, and the average evaporation rate of the BFM device with integrated EFAE function is 0.12 mg/s. Accordingly, the user of this VOG system can feel the generation of odor within 3 s, while the switching of different odor channels can be wirelessly controlled by a mobile phone. This VOG system enhances the user's immersive and interactive experience for virtual reality technology. The similar system composed of UVE‐TENG, reed switch, BFM and EFAE devices also has potential application value in assisted breathing treatment and nasal delivery.

show abstract

What does the nose know? Olfactory function predicts social network size in human

Cited by 47 publications

References 44 publications

Olfactory function and the social lives of older adults: a matter of sex

Olfactory function and the social lives of older adults: a matter of sex

Otolaryngic sensory loss as a measure of frailty among older US adults

Self‐powered virtual olfactory generation system based on bionic fibrous membrane and electrostatic field accelerated evaporation

Contact Info

Product

Resources

About