What are the unmet supportive care needs of men affected by penile cancer? A systematic review of the empirical evidence

Paterson, Catherine; Primeau, Charlotte; Bowker, Mallory; Jensen, Bente Thoft; MacLennan, Steven; Yuan, Yuhong; N’Dow, James

doi:10.1016/j.ejon.2020.101805

Cited by 28 publications

(39 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The need for better risk factor assessment and subsequent counseling is obvious, as recently pointed out by Paterson and coworkers. 10 They systemically reviewed the literature and evaluated the evidence for unmet supportive care needs of men…”

Section: Article In Pressmentioning

confidence: 99%

See 1 more Smart Citation

Health-Related Quality of Life, Self-esteem and Sexual Functioning Among Patients Operated for Penile Cancer – A Cross-sectional Study

Harju

Pakarainen

Vasarainen

et al. 2021

The Journal of Sexual Medicine

View full text Add to dashboard Cite

Background: Penile cancer surgery affects physical, psychological, and sexual well-being, but the patient-and treatment-related factors predisposing to worse health-related quality of life (HRQoL) have not been well characterized. Aim: We report treatment-related HRQoL changes among penile cancer survivors compared to the general population and the specific deficits that have the most profound effect, and we identify patient-related factors that predispose to a worse perceived HRQoL. Methods: Patients (n = 107) who underwent operations for invasive penile cancer in two Finnish university hospitals from 2009 to 2019 were sent the Patient Reported Outcomes (PROs) questionnaire designed to measure HRQoL, self-esteem, overall sexual functioning, erections, and change in sexual function. We collected clinical information and socio-demographic characteristics, including age, partner status, children, vocational education, and employment status. Associations between patient-and treatment-related factors and HRQoL were analyzed using descriptive statistics and non-parametric tests. Linear regression models were used to compare the HRQoL differences between patients with penile cancer and the age-standardized average for the Finnish population. Outcomes: A generic measure of HRQoL (15D), the Rosenberg Self-Esteem Scale, Overall Sexual Functioning Questionnaire, the Erection Hardness Score, and self-reported change in sexual functioning. Results: Low scores in overall sexual functioning, erectile function, and changes in sexual functioning were associated with a lower HRQoL. An association was found between HRQoL and age, educational level, employment status, and place of residence. The HRQoL had a negative correlation with age. Patients with a high educational level, who were employed, or who lived in urban areas reported higher HRQoL. The mean HRQoL of penile cancer survivors was significantly lower than the age-standardized average HRQoL of the Finnish population. Clinical Implications: Enhanced support and counseling is needed among penile cancer patients to improve the HRQoL during survivorship. Strengths & Limitations: A nationwide sample with detailed information allowed comparisons of HRQoL between penile cancer patients and the general population. Due to cross-sectional nature of the study, the time between the surgery and the study intervention was heterogeneous, and this may have affected the results. Conclusion: Penile cancer patients exhibit significant physical and psychological dysfunction, and the lack of sexual activity in general is what most compromises the QoL of penile cancer survivors. Harju E, Pakarainen T, Vasarainen H, et al. Health-Related Quality of Life, Self-esteem and Sexual Functioning Among Patients Operated for Penile Cancer − A Cross-sectional Study. J Sex Med 2021;XX:XXX−XXX.

show abstract

Section: Article In Pressmentioning

confidence: 99%

“…7 A recent systematic review highlights this shortcoming and reports numerous unmet needs experienced by patients with PC. 10 A need therefore exists for further investigations into the specific deficits that have the most profound effects on the QoL of patients with PC.…”

Section: Introductionmentioning

confidence: 99%

Health-Related Quality of Life, Self-esteem and Sexual Functioning Among Patients Operated for Penile Cancer – A Cross-sectional Study

Harju

Pakarainen

Vasarainen

et al. 2021

The Journal of Sexual Medicine

View full text Add to dashboard Cite

show abstract

“…Lymph node involvement on presentation means a worse prognosis in terms of morbidity and mortality. 9,10,12 The normal lymphatic drainage of a primary penile cancer is to the inguinal lymph nodes. Palpating the lymph nodes for changes can be unreliable, even when impalpable there is a 25% likelihood of micro-mets and these can be missed by fine-needle aspiration.…”

Section: Why Men With Penile Cancer May Be At Risk Of Lymphedemamentioning

confidence: 99%

“…8 However, it remains relatively rare, with an overall incidence of approximately 1 per 100 000 8 and slightly higher in some parts of Asia, Africa, and South America. 9 The devastating impact of penile cancer and its treatment has been described [10][11][12] but, with the exception of Gopman et al, 3 the acknowledgment of the risk of genital lymphoedema is strikingly absent.…”

mentioning

confidence: 99%

Recognizing genital lymphoedema after penile cancer

Noble-Jones

Thomas

2021

Int J of Uro Nursing

View full text Add to dashboard Cite

Lymphadenectomy for penile cancer treatment increases the risk of genital lymphoedema. There is very little acknowledgment of the risk of genital lymphoedema after penile cancer or its treatment in current literature. Genital lymphoedema is most responsive to treatment in the early stages before irreversible skin changes occur; therefore, early identification would benefit patients. A urology clinic-based study found an assumption among health care professionals that in patients with a broad range of genital cancers, post-operative acute genital oedema would resolve on its own, meaning vigilance for chronic lymphoedema was low. It is unclear whether vigilance for lymphoedema is any higher in specialist centres treating penile cancer. This article describes some of the challenges of recognizing genital lymphoedema in an urooncology caseload and specifically in relation to penile cancer. An example case report of penile cancer-related lymphoedema is described and puts this within the context of two relevant studies, one in a single uro-oncology centre and the other a wider interna-

show abstract

“…Однако исследования в этой области немногочисленны и чаще всего посвящены оценке качества жизни пациентов в связи с различными видами лечения, в первую очередь хирургического (см., напр., Draeger et al, 2018). При этом исследователями признается необходимость дальнейшего изучения эмоционального состояния, личностных особенностей и межличностных отношений пациентов (Paterson et al, 2020).…”

Section: обсуждение результатовunclassified

Psychological Characteristics and Quality of Life of Patients with Penile Cancer: Pilot Study on a Russian Sample

Щелкова

Usmanova

Iakovleva

et al. 2021

RUDN J. Psychol. Pedagog.

View full text Add to dashboard Cite

Research into the psychological aspects of oncological diseases is nowadays relevant and widespread; however, there are very few studies in patients with penile cancer (PC). Therefore, the purpose of this pilot study is to investigate the psychological characteristics and quality of life of patients with PC for further organization of psychological counseling. The study included 17 male patients (mean age 49.0 3.76 years) of the N.N. Blokhin National Medical Research Center of Oncology. The following techniques were used: Hospital Anxiety and Depression Scale (HADS), Big Five Inventory (BFI), Ways of Coping Questionnaire (WCQ), Purpose in Life Test (PLT), Quality of Life of Cancer Patients (EORTC QLQ-C30). The patients overall health status was assessed by D.A. Karnofskys scale; a specific psychological structured interview was also conducted. The emotional state of most patients is characterized by low indexes of anxiety and depression. Most of them are purposeful, organized, emotionally stable, unwilling to form trusting relationships. They have high rates of life meaningfulness, a normative level of internality and a decreased purpose in life indicator. The patients are not prone to active and conscious overcoming stress compared to healthy men. The indexes of quality of life, as well as the rates of its specific parameters (cognitive, physical and emotional activity) in the studied group of patients exceed the same values in patients with different tumor localizations and are not consistent with the objectively estimated condition. Health-related quality of life is largely determined by the characteristics of patients value system, especially in oncological diseases that are related not only to a vital threat, but also to deep personal experiences, including the experience of patients male identity.

show abstract

What are the unmet supportive care needs of men affected by penile cancer? A systematic review of the empirical evidence

Cited by 28 publications

References 35 publications

Health-Related Quality of Life, Self-esteem and Sexual Functioning Among Patients Operated for Penile Cancer – A Cross-sectional Study

Health-Related Quality of Life, Self-esteem and Sexual Functioning Among Patients Operated for Penile Cancer – A Cross-sectional Study

Recognizing genital lymphoedema after penile cancer

Psychological Characteristics and Quality of Life of Patients with Penile Cancer: Pilot Study on a Russian Sample

Contact Info

Product

Resources

About