What are the Predictors of Death in Patients With Cranio-Cervical Artery Dissection?

Abstract

Severe disability at admission was a mortality predictor in both CAD and VAD. Although the initial severity of stroke is reportedly related to poor outcomes in patients with CCAD, it has not previously been directly identified as a predictor of mortality in patients with CAD or VAD.

Extracranial and intracranial artery dissections: Experiences from a tertiary referral center

“…The vascular wall vulnerability is important in the pathophysiology of especially spontaneous cases. The association between the connective tissue disorders and dissections supports this knowledge 5 . In a study conducted with 65 cases, the skin biopsy was confirmed the connective tissue disease in 55% of cases 6 .…”

“…The recurrence was more common in young patients and the prognosis is better in this group. When all dissections were considered, 88% of cases had completed recovery with early diagnosis and treatment and the mortality was seen in only 10% of the cases 5,16,17 . There was no mortality in our cases and the rate of total recovery was 89.7% which was consistent with the literature.…”

“…The abnormalities in arterial wall structure are blamed in dissection pathophysiology with consistently higher rate of connective tissue disease in these patients. The weaknesss in arterial walls, whether traumatic or not, increases the risk of dissections 5 . The diseases causing vessel wall pathology such as Marfan syndrome, cystic medial degeneration, fibromuscular dysplasia, Ehlers Danlos syndrome, osteogenesis imperfecta type 1 and other connective tissue diseases are blamed in dissection etiology 16,20 .…”

Revaskularisasi pada Diseksi Arteri Karotis Setelah Pengobatan dengan Novel Oral Anticoagulan (NOAC) pada Stoke Infark Akut

“…Sekitar 1,7% pasien yang mengalami diseksi arteri karotis akan mengalami stroke iskemik dalam waktu 12 minggu, dan seringkali muncul pada minggu kedua. [2][3][4][5] Pada pasien dengan diseksi arteri di servikal, kejadian stroke paling sering muncul akibat adanya emboli yang berasal dari trombus yang lepas pada arteri yang mengalami diseksi. Kemungkinan lain penyebab stroke pada diseksi arteri karotis adalah terjadinya infark pada daerah watershed yang muncul akibat hipoperfusi, walaupun kejadian ini sangatlah jarang.…”