2003
DOI: 10.1152/ajpheart.01090.2002
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Abstract: We studied the effects of a hypocaloric diet (D, n = 24, age: 32.2 +/- 1.4 yr, body mass index: 34.7 +/- 0.5 kg/m2) and a hypocaloric diet associated with exercise training (D + T, n = 25, age: 32.3 +/- 1.3 yr, body mass index: 32.9 +/- 0.4 kg/m2) on muscle metaboreflex control, muscle sympathetic nerve activity (MSNA, microneurography), blood pressure, and forearm blood flow (plethysmography) levels during handgrip exercise at 10% and 30% of maximal voluntary contraction in normotensive obese women. An additi… Show more

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Cited by 120 publications
(121 citation statements)
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“…Weight loss is associated with a reduction in MSNA (Grassi et al, 1998, Trombetta et al, 2003, Straznicky et al, 2005 and whole body NE spillover (Schwartz et al, 1990). Unfortunately, there is currently no information available on whether weight loss lowers SNS activity to the kidney or other tissues/organs.…”
Section: Weight Change and Sympathetic Neural Behaviormentioning
confidence: 99%
“…Weight loss is associated with a reduction in MSNA (Grassi et al, 1998, Trombetta et al, 2003, Straznicky et al, 2005 and whole body NE spillover (Schwartz et al, 1990). Unfortunately, there is currently no information available on whether weight loss lowers SNS activity to the kidney or other tissues/organs.…”
Section: Weight Change and Sympathetic Neural Behaviormentioning
confidence: 99%
“…This cuff inflated every 30 s, as described previously. 18,19 Body composition determination. Fat body mass and lean body mass parameters were assessed by whole-body dual-energy X-ray absorption anthropometry with HOLOGIC QDR-2000 densitometer.…”
Section: Study Populationmentioning
confidence: 99%
“…Reduced muscle blood flow and forearm vascular conductance have been well characterized in obese children, adolescents and adults 5,10,18 . Our findings are consistent with these findings in the literature, since we also found that the vascular conductance and blood flow in the forearm muscles are decreased in obese children.…”
Section: Baseline Forearm Vascular Conductance (Units) Eutrophic Obesmentioning
confidence: 99%
“…Obese people present baroreflex dysfunction 4 , increased peripheral vascular resistance 5 , high oxidative stress 6 , as well as increased cardiac and muscular sympathetic activity 7,8 . These changes may lead to increased levels of blood pressure and decreased blood flow to muscles.…”
Section: Introductionmentioning
confidence: 99%
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