Weekly intramuscular methotrexate in the treatment of low-risk gestational trophoblastic neoplasia

Abstract

Weekly methotrexate without dose escalation may be an appropriate option for primary chemotherapy of patients with LRGTN.

The WHO score predicts treatment outcome in low risk gestational trophoblastic neoplasia patients treated with weekly intramuscular methotrexate

“…Twenty one of 33 patients (63.6%) were cured with first line therapy. [19] In another study Kang et al used weekly MTX 50 mg/m 2 without dose escalation for 48 patients with LRGTN. Their primary remission rate was 70.8%.…”