Water as a sensor of weak impacts on biological systems

Lobyshev, Valentin I.

doi:10.1007/s12551-023-01120-2

Cited by 6 publications

(3 citation statements)

References 83 publications

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“…Recently, there has been a growing interest in the study of the properties of highly diluted aqueous solutions [1], as well as water exposed to weak and strong physical factors [2][3][4][5]. The preparation of highly diluted substances is accompanied by serial (tenfold or centesimal) dilution with vigorous shaking at each dilution step [6]. Such high dilutions (HDs) can affect various physico-chemical and biological parameters in experimental models, although the initial substance in them is contained in extremely low concentrations or is nearly absent [7,8].…”

Section: Introductionmentioning

confidence: 99%

Weak Magnetic Fields Regulate the Ability of High Dilutions of Water to Enhance ROS Production by Neutrophils

Fesenko,

Yablokova,

Novikov

2024

Applied Sciences

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The influence of magnetic fields on the physico–chemical properties of water and aqueous solutions is well known. We have previously shown that weak combined magnetic fields with a 60 µT static component and a 100 nT (at 12.6 Hz) variable component are able to activate neutrophils, both directly and indirectly, through water pre-incubated in these fields. The ability to influence the activity of neutrophils was retained in serial dilutions of water, but only when a mechanical effect (shaking) was applied at each dilution step. Here, we confirm that combined magnetic fields are required for the formation of the stimulatory activity of water on ROS production by neutrophils. For the first time, we determined the threshold values of a constant magnetic field (at least 350–550 nT) necessary to maintain this activity in a series of successive dilutions. Additionally, the biophysical properties of various dilutions appeared to be not identical. This confirms that the number of technological steps (successive dilutions with physical influence) is a key factor that determines the activity of highly diluted samples.

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Section: Introductionmentioning

confidence: 99%

Weak Magnetic Fields Regulate the Ability of High Dilutions of Water to Enhance ROS Production by Neutrophils

Fesenko,

Yablokova,

Novikov

2024

Applied Sciences

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“…In Lobyshev V.I. 's report, arguments have been made in favor of the fact that water and the aquatic environment are sensors of weak interactions [1].…”

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confidence: 99%

The Best Material from the VII Congress of Russian Biophysicists

Anashkina,

Dzhimak

2024

IJMS

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“…It is known that certain structural changes can occur in water after exposure to both mechanical [29,[32][33][34][35] and electromagnetic [36][37][38] vibration effects. Since the vibration effect during the preparation of high dilutions is mediated by the IS, specific structural rearrangements are eventually accumulated in the solvent.…”

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confidence: 99%

The Supramolecular Matrix Concept

Epstein

2023

Symmetry

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It has been established that dilutions of a variety of substances, when exposed to vibration in the process of their preparation, acquire not only new structural characteristics in the form of nano-associates but also new physical properties, regardless of the presence of the initial substance. One of the most important properties of these dilutions is the ability to modify the physico–chemical and biological activity of the initial substance as well as exert non-contact, “distant”, effects. Here, we propose a novel hypothesis that the basis of modifying activity is the transformation of target molecules to a more harmonious (symmetrical) state supported by a supramolecular matrix, a structural unit of a structured space.

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Water as a sensor of weak impacts on biological systems

Cited by 6 publications

References 83 publications

Weak Magnetic Fields Regulate the Ability of High Dilutions of Water to Enhance ROS Production by Neutrophils

Weak Magnetic Fields Regulate the Ability of High Dilutions of Water to Enhance ROS Production by Neutrophils

The Best Material from the VII Congress of Russian Biophysicists

The Supramolecular Matrix Concept

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