Wart Relapses at the Edges of Therapeutic Cantharidin Blisters

Findlay, G. H.

doi:10.1001/archderm.1959.01560230075019

Cited by 7 publications

(6 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The other reported cases of doughnut warts 4‐8 were presented without any therapeutic interventions. However, some authors suggest different lines of therapy such as erbium‐yag (yttrium‐argon‐garnet) laser ablation of the wart with a 5‐mm rim of normal epidermis.…”

Section: Discussionmentioning

confidence: 99%

“…Another explanation is that doughnut warts might represent a form of Koebner phenomenon as a result of latent activation of the potentially infected cell by trauma mediated by the destructive treatment modality 3‐6 . Furthermore, cryotherapy is associated with the disruption of cell membranes and organelles caused by the intracellular and extracellular formation of ice.…”

Section: Discussionmentioning

confidence: 99%

“…Doughnut warts have the potential to be both embarrassing and frustrating for both patients and physicians. 8,11 Doughnut warts were reported after topical cantharidin application [5][6][7] and after cryosurgery. 8 In this study, we present 15 cases with doughnut warts, which developed in all patients after a variable number of cryotherapy sessions except for electrocautery in one patient.…”

Section: Re Sultsmentioning

confidence: 99%

“…3,15 Another explanation is that doughnut warts might represent a form of Koebner phenomenon as a result of latent activation of the potentially infected cell by trauma mediated by the destructive treatment modality. [3][4][5][6] Furthermore, cryotherapy is associated with the disruption of cell membranes and organelles caused by the intracellular and extracellular formation of ice. This leads to the release of HPV from damaged cells, resulting, in rare instances, in the formation of the doughnut warts at the periphery of the already treated wart.…”

Section: Re Sultsmentioning

confidence: 99%

“…Doughnut warts, also called ring or annular warts, are a distinctive type of recurrent warts characterized by central clearing and annular recurrence. They are often seen on the feet and hands of patients whose warts have been treated with destructive chemical or physical modalities such as cantharidin and cryotherapy 4‐8 . To the best of our knowledge, only 8 cases of doughnut warts have been reported in the literature; one of them only has received medical treatment 6 …”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Successful treatment of doughnut warts with intralesional Candida antigen immunotherapy

Nofal

Fouda

Aboelwafa

et al. 2020

J of Cosmetic Dermatology

View full text Add to dashboard Cite

Warts are very common viral infections of the skin caused by human papilloma virus (HPV). Although warts are mostly asymptomatic and nearly half of the cutaneous warts regress within 1-2 years, treatment is often sought due to social stigmatization, pain, and irritation. 1 First-line treatments for cutaneous warts include topical salicylic acid and cryotherapy (individually or as combined modalities), which are considered the standard conventional destructive modalities for the treatment of warts. Other therapeutic modalities that have been studied for the use in refractory warts include imiquimod, dinitrochlorobenzene, 5-fluorouracil, immunotherapy, duct tape, photodynamic therapy, pulsed dye laser, and surgical excision. 2 Adverse effects of conventional destructive treatments may include pain, infection, scarring, dyspigmentation, and recurrence that might be as high as 30%. Recurrence has been attributed to the recrudescence of latent virus adjacent to the original wart. 3 Doughnut warts, also called ring or annular warts, are a distinctive type of recurrent warts characterized by central clearing and annular recurrence. They are often seen on the feet and hands of patients whose warts have been treated with destructive chemical or physical modalities such as cantharidin and cryotherapy. 4-8 To the best of our knowledge, only 8 cases of doughnut warts have been reported in the literature; one of them only has received medical treatment. 6

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%