Vulnerability to Heat-Related Mortality

Stafoggia, Massimo; Forastiére, Francesco; Agostini, Daniele; Biggeri, Annibale; Bisanti, Luigi; Cadum, Ennio; Caranci, Nicola; Donato, Francesca De'; Lisio, Sara De; Maria, Moreno De; Michelozzi, Paola; Miglio, Rossella; Pandolfi, Pier Paolo; Picciotto, Sally; Rognoni, M; Russo, Antonio; Scarnato, Corrado; Perucci, Carlo A.

doi:10.1097/01.ede.0000208477.36665.34

Cited by 358 publications

(186 citation statements)

References 36 publications

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“…Given the comparability between the study of Houston and New York City and the corroborating study by Stafoggia et al, 30 the current results of the comparable studies support the likelihood that there is an increased risk of OHCA with exposure to ozone.…”

Section: Association Between Ozone and Ohcasupporting

confidence: 76%

“…We included apparent temperature in our conditional logistic regression model by using a nonparametric smoothing spline of degree 3 with 4 knots optimally chosen. [27][28][29][30][31] The EMS data, in which the call time acts as the time of the OHCA, provided the ability for an analysis on the hourly as opposed to the daily scale typically assessed. However, because both cardiac arrest and pollutant data may have diurnal patterns, temporal confounding must be considered.…”

Section: Statistical Methodologymentioning

confidence: 99%

“…The results found in New York City and Houston are consistent with findings from an important case-crossover study with a more encompassing health end point. Stafoggia et al 30 examined susceptibility factors to ozone mortality. Of interest to our objective is their examination of ozone-related mortality in those with preexisting cardiovascular conditions.…”

Section: Association Between Ozone and Ohcamentioning

confidence: 99%

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A Case-Crossover Analysis of Out-of-Hospital Cardiac Arrest and Air Pollution

2013

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Background— Evidence of an association between the exposure to air pollution and overall cardiovascular morbidity and mortality is increasingly found in the literature. However, results from studies of the association between acute air pollution exposure and risk of out-of-hospital cardiac arrest (OHCA) are inconsistent for fine particulate matter, and, although pathophysiological evidence indicates a plausible link between OHCA and ozone, none has been reported. Approximately 300 000 persons in the United States experience an OHCA each year, of which >90% die. Understanding the association provides important information to protect public health. Methods and Results— The association between OHCA and air pollution concentrations hours and days before onset was assessed by using a time-stratified case-crossover design using 11 677 emergency medical service–logged OHCA events between 2004 and 2011 in Houston, Texas. Air pollution concentrations were obtained from an extensive area monitor network. An average increase of 6 µg/m 3 in fine particulate matter 2 days before onset was associated with an increased risk of OHCA (1.046; 95% confidence interval, 1.012–1.082). A 20-ppb ozone increase for the 8-hour average daily maximum was associated with an increased risk of OHCA on the day of the event (1.039; 95% confidence interval, 1.005–1.073). Each 20-ppb increase in ozone in the previous 1 to 3 hours was associated with an increased risk of OHCA (1.044; 95% confidence interval, 1.004–1.085). Relative risk estimates were higher for men, blacks, or those aged >65 years. Conclusions— The findings confirm the link between OHCA and fine particulate matter and introduce evidence of a similar link with ozone.

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Section: Association Between Ozone and Ohcasupporting

confidence: 76%

Section: Statistical Methodologymentioning

confidence: 99%

Section: Association Between Ozone and Ohcamentioning

confidence: 99%

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A Case-Crossover Analysis of Out-of-Hospital Cardiac Arrest and Air Pollution

2013

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“…Bei alldem ist das Zielpublikum zu bedenken: bei Hitzewellen sind ältere, allein stehende und kranke Personen sowie soziale Randgruppen besonders gefährdet (O'Neill et al, 2003;Khalaj et al, 2010;Reid et al, 2009;English et al, 2009;Stafoggia et al, 2006Stafoggia et al, , 2008Stafoggia et al, , 2009Semenza, 1996;Kovats, 2006;Foroni et al, 2007;Hajat et al, 2010 …”

Section: Hitzewarnungenunclassified

Kapitel 4: Gesundheit, Tourismus

Moshammer¹,

Prettenthaler²,

Damm³

et al. 2014

Österreichischer Sachstandsbericht Klimawandel 2014

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“…A textbook example is the contrasted effect of ECE according to age in human populations. Specifically, during the 2003 heatwave in Europe, more than 70 000 human deaths were recorded, with the most vulnerable persons being young and older individuals [29], which affected the age pyramid.…”

Section: Introductionmentioning

confidence: 99%

Effect of extreme sea surface temperature events on the demography of an age-structured albatross population

Pardo

Jenouvrier

Weimerskirch

et al. 2017

Phil. Trans. R. Soc. B

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One contribution of 14 to a theme issue 'Behavioural, ecological and evolutionary responses to extreme climatic events'. Climate changes include concurrent changes in environmental mean, variance and extremes, and it is challenging to understand their respective impact on wild populations, especially when contrasted age-dependent responses to climate occur. We assessed how changes in mean and standard deviation of sea surface temperature (SST), frequency and magnitude of warm SST extreme climatic events (ECE) influenced the stochastic population growth rate log(l s ) and age structure of a black-browed albatross population. For changes in SST around historical levels observed since 1982, changes in standard deviation had a larger (threefold) and negative impact on log(l s ) compared to changes in mean. By contrast, the mean had a positive impact on log(l s ). The historical SST mean was lower than the optimal SST value for which log(l s ) was maximized. Thus, a larger environmental mean increased the occurrence of SST close to this optimum that buffered the negative effect of ECE. This 'climate safety margin' (i.e. difference between optimal and historical climatic conditions) and the specific shape of the population growth rate response to climate for a species determine how ECE affect the population. For a wider range in SST, both the mean and standard deviation had negative impact on log(l s ), with changes in the mean having a greater effect than the standard deviation. Furthermore, around SST historical levels increases in either mean or standard deviation of the SST distribution led to a younger population, with potentially important conservation implications for black-browed albatrosses.This article is part of the themed issue 'Behavioural, ecological and evolutionary responses to extreme climatic events'.

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Vulnerability to Heat-Related Mortality

Abstract: Subsets of the population that are particularly vulnerable to high summer temperatures include the elderly, women, widows and widowers, those with selected medical conditions, and those staying in nursing homes and healthcare facilities.

Cited by 358 publications

References 36 publications

A Case-Crossover Analysis of Out-of-Hospital Cardiac Arrest and Air Pollution

A Case-Crossover Analysis of Out-of-Hospital Cardiac Arrest and Air Pollution

Kapitel 4: Gesundheit, Tourismus

Effect of extreme sea surface temperature events on the demography of an age-structured albatross population

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