2019
DOI: 10.1055/s-0039-1694061 View full text |Buy / Rent full text
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Abstract: Background We investigated the postoperative upstaging of stage I and II lung adenocarcinoma patients to identify useful predictors for accurate staging. Methods We retrospectively reviewed data from 80 consecutive patients undergoing lobectomy and mediastinal lymph node dissection for clinical stage I and II lung adenocarcinomas. We evaluated clinical variables, including the preoperative serum carcinoembryonic antigen (CEA), tumor diameter, consolidation-to-tumor ratio (CTR), maximum standardized… Show more

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“…We split all the nodules into 2 groups, namely a growth group and nongrowth group, based on the relative position of their VDTs compared to cut-off values predefined, where the cut-off for ground glass nodules (GGN, consisting of pure GGN and part-solid nodules) ( 22) was 1,500 days and that for solid nodule was 500 days. The CTR were computed only for GGN by dividing the nodule volume by the consolidation volume where the nodule regions with a CT value higher than −300 HU were considered as consolidations (23). For CTR, 50% was used as the cut-off.…”
Section: Nodule Characterizationmentioning
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“…We split all the nodules into 2 groups, namely a growth group and nongrowth group, based on the relative position of their VDTs compared to cut-off values predefined, where the cut-off for ground glass nodules (GGN, consisting of pure GGN and part-solid nodules) ( 22) was 1,500 days and that for solid nodule was 500 days. The CTR were computed only for GGN by dividing the nodule volume by the consolidation volume where the nodule regions with a CT value higher than −300 HU were considered as consolidations (23). For CTR, 50% was used as the cut-off.…”
Section: Nodule Characterizationmentioning
“…We previously reported no lymph node involvement in GGO-dominant lung cancer, though no significant survival superiority was observed on multivariate analyses (10). We also found the usefulness of volume-based CTR with 3-dimensional assessments for accurate pathological staging of lymph node metastasis in stage I and II adenocarcinoma (11). Tumor diameter is classified in units of 1 cm in the current UICC-TNM classification version 8, which is well recognized to predict postoperative survival outcomes (12).…”
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