“…Lactam with 5 to 7 membered structures (γ-, δ-, σ-lactam) may have activities against degenerative diseases such as Parkinson's, Alzheimer's, anti-cancer, anti-viral, and anti-fungal agents ( Albrecht et al, 2014 , Assaf et al, 2014 , Prando and Batistella, 2008 ). The probable action of these compounds in neurodegenerative diseases, along with the presence of maleimide, caffeine, and phenolics may indicate a way to elucidate the descriptions of physical and mental well-being reported by elderly people, who consume seeds and pulp from caferana fruits ( Fraga et al, 2020 , Peixoto et al, 2017 ).…”