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Cited by 20 publications
(7 citation statements)
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References 45 publications
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“…Isoflurane arm (0.3–0.8%) had a significantly lower mortality than propofol/midazolam arm. Isoflurane arm also had shorter ventilator-support, in line with other studies that VA group experienced earlier extubation (sevoflurane 0.5–1.0%, isoflurane 0.1–0.6%) [60,6466]. Early extubation may potentially reduce ventilator-associated complications such as atelectasis, volutrauma and pneumonia.…”
Section: Volatile Anesthetics As Sedatives In Patients With Ardssupporting
confidence: 80%
See 1 more Smart Citation
“…Isoflurane arm (0.3–0.8%) had a significantly lower mortality than propofol/midazolam arm. Isoflurane arm also had shorter ventilator-support, in line with other studies that VA group experienced earlier extubation (sevoflurane 0.5–1.0%, isoflurane 0.1–0.6%) [60,6466]. Early extubation may potentially reduce ventilator-associated complications such as atelectasis, volutrauma and pneumonia.…”
Section: Volatile Anesthetics As Sedatives In Patients With Ardssupporting
confidence: 80%
“…In general, VAs at one-third of doses for general anesthesia would be adequate to achieve sedation [116]. This is illustrated in the studies cited above [22,60,6366]. However, VAs at much higher concentrations are required when deeper sedation is indicated [116].…”
Section: Volatile Anesthetics As Sedatives In Patients With Ardsmentioning
confidence: 99%
“…All forms of anesthesia are able to modulate the immune system and affect innate and adaptive immunity, but volatile agents possess favorable properties [98,108,131,132]. Multiple studies have shown that sedation with volatile anesthetics over midazolam and propofol was associated with a decrease in time of mechanical ventilation [133][134][135][136][137]. Early extubation is very beneficial in terms of reduction in ventilator-associated complications like volutrauma, atelectasis, and pneumonia [129].…”
Section: Favorable Specifics Of Volatile Anesthetics In Ards Sedationmentioning
confidence: 99%
“…After the introduction of volatile sedation, there have been several recent meta-analyses in ICU patients [ 45 , 46 ] and postcardiac surgical patients. [ 47 ] However, these meta-analyses included volatile sedation using a conventional vaporizer, which had significantly slow anesthetic wash-out times compared with the new anesthetic reflectors using the same fresh gas flow rates; this is because the conventional vaporizer could not be removed from the breathing circuit.…”
Section: Discussionmentioning
confidence: 99%