1993
DOI: 10.1001/archderm.129.5.600
|View full text |Cite
|
Sign up to set email alerts
|

Vitiliginous vs pigmented skin response to intradermal administration of interferon gamma

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
3
0

Year Published

1994
1994
2015
2015

Publication Types

Select...
6
2

Relationship

1
7

Authors

Journals

citations
Cited by 9 publications
(3 citation statements)
references
References 0 publications
0
3
0
Order By: Relevance
“…In addition, CXCR3 was demonstrated to be essential for autoreactive T cell accumulation in the skin and subsequent depigmentation in a mouse model, implicating this chemokine pathway as functionally required for vitiligo. 21,32) We then evaluated the effect of EGCG on the expression of CD11a, CXCR3, and CCR2 in activated human T cells. Western blot analysis revealed that EGCG treatment for 24 h decreased the expression of CD11a, CXCR3, and CCR2 in Jurkat, a CD4+ T leukemia cell line, in a dose-dependent manner (Fig.…”
Section: -31)mentioning
confidence: 99%
“…In addition, CXCR3 was demonstrated to be essential for autoreactive T cell accumulation in the skin and subsequent depigmentation in a mouse model, implicating this chemokine pathway as functionally required for vitiligo. 21,32) We then evaluated the effect of EGCG on the expression of CD11a, CXCR3, and CCR2 in activated human T cells. Western blot analysis revealed that EGCG treatment for 24 h decreased the expression of CD11a, CXCR3, and CCR2 in Jurkat, a CD4+ T leukemia cell line, in a dose-dependent manner (Fig.…”
Section: -31)mentioning
confidence: 99%
“…IFN-y induces HLA-DR expression in various organs including the skin [20][21][22]. Failure of aged skin keratino cytes to express HLA-DR after intradermal injection was not observed when the skin was grafted onto nude mice, suggesting that disconnecting the skin from the aged envi ronment releases the keratinocytes from an as yet unidenti fied inhibitory factor.…”
Section: Discussionmentioning
confidence: 99%
“…Its etiology is unknown, and the symptoms probably result from a variety of pathogenic alterations of the immune and neural systems, and of melanocyte structure and function (1)(2)(3)(4)(5)(6)(7)(8).…”
Section: Introductionmentioning
confidence: 99%