Vitamin K prophylaxis and childhood cancer

Ross, Julie A.; Davies, Stella M.

doi:10.1002/(sici)1096-911x(200006)34:6<434::aid-mpo11>3.0.co;2-x

Cited by 39 publications

(15 citation statements)

References 33 publications

(42 reference statements)

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“…10 While VKBD is a rare disease, the consequences are severe. 1,11 The Australian Pediatric Surveillance Unit (APSU) reported six confirmed cases of VKBD from 2007 to 2008, the majority of which were late-onset VKDB. 5 Of those with a late onset, more than half had liver disease.…”

Section: Discussionmentioning

confidence: 99%

Maternal and infant characteristics by mode of vitamin K prophylaxis administration

Khambalia¹,

Roberts²,

Bowen

et al. 2012

J Paediatrics Child Health

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Section: Discussionmentioning

confidence: 99%

Maternal and infant characteristics by mode of vitamin K prophylaxis administration

Khambalia¹,

Roberts²,

Bowen

et al. 2012

J Paediatrics Child Health

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“…Ross and Davies reviewed the epidemiologic studies and found no evidence for the originally suggested relationship between IM vitamin K prophylaxis and the development of childhood cancer. 25 …”

mentioning

confidence: 99%

Prophylactic Dosing of Vitamin K to Prevent Bleeding

Witt¹,

Kvist²,

Jørgensen

et al. 2016

Pediatrics

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also, on behalf of the Netherlands Study group of Biliary Atresia Registry (NeSBAR) abstract BACKGROUND AND OBJECTIVES: Based on a high incidence of Vitamin K deficiency bleeding (VKDB) in breastfed infants with thus far unrecognized cholestasis, such as biliary atresia (BA), the Dutch regimen to prevent VKDB in breastfed infants was changed from a daily oral dosage of 25 μg to 150 μg vitamin K. Infants continued to receive 1 mg of vitamin K orally at birth. We compared the efficacy of the 150-μg regimen with the 25-μg regimen and with the Danish regimen of a single intramuscular (IM) dose of 2 mg vitamin K at birth.

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“…vitamin K has been a matter of dispute. The review by Ross and Davies (15) concludes that no relation has been proven. Increased risk of solid tumours is excluded.…”

Section: Discussionmentioning

confidence: 99%