Vitamin A Supplementation for Retinitis Pigmentosa

Abstract

The relationship between rod perimetric thresholds and full-field rod ERGs in retinitis pigmentosa.

Molecular Mechanisms of Rhodopsin Retinitis Pigmentosa and the Efficacy of Pharmacological Rescue

“…47 Finally, vitamin A palmitate slightly slows the progressive decay of electroretinogram (ERG) responses in RP patients. [48][49][50] These studies support the use of pharmacological rescue in rhodopsin RP. However, it is unknown whether this strategy and the protein-misfolding disease model on which it is based are relevant to only a few RP rhodopsins or are more widely applicable.…”

Molecular Mechanisms of Rhodopsin Retinitis Pigmentosa and the Efficacy of Pharmacological Rescue

“…47 Finally, vitamin A palmitate slightly slows the progressive decay of electroretinogram (ERG) responses in RP patients. [48][49][50] These studies support the use of pharmacological rescue in rhodopsin RP. However, it is unknown whether this strategy and the protein-misfolding disease model on which it is based are relevant to only a few RP rhodopsins or are more widely applicable.…”

Vitamin A Intake and Hip Fractures Among Postmenopausal Women

“…However, multivitamins contain other essential nutrients and have been associated with lower risk of coronary disease, 38 colon cancer, 39 and breast cancer 40 in this same cohort. Also, the findings from this study do not imply that supplementation with vitamin A should be discontinued when used for conditions such as retinitis pigmentosa, for which benefits have been documented, 41 although monitoring of bone health may be appropriate.…”

Efficacy of Oral Valproic Acid in Patients with Retinitis Pigmentosa

“…The median logMAR BCVA improved from 1.8 1–3 in group 1 at baseline to 1.3 (0.6–1.3) at 1-year follow-up in group 1 (30 eyes). This change was statistically significant ( P <0.001).…”

Molecular Mechanisms of Rhodopsin Retinitis Pigmentosa and the Efficacy of Pharmacological Rescue

“…47 Finally, vitamin A palmitate slightly slows the progressive decay of electroretinogram (ERG) responses in RP patients. [48][49][50] These studies support the use of pharmacological rescue in rhodopsin RP. However, it is unknown whether this strategy and the protein-misfolding disease model on which it is based are relevant to only a few RP rhodopsins or are more widely applicable.…”

Vitamin A Intake and Hip Fractures Among Postmenopausal Women

“…However, multivitamins contain other essential nutrients and have been associated with lower risk of coronary disease, 38 colon cancer, 39 and breast cancer 40 in this same cohort. Also, the findings from this study do not imply that supplementation with vitamin A should be discontinued when used for conditions such as retinitis pigmentosa, for which benefits have been documented, 41 although monitoring of bone health may be appropriate.…”

Efficacy of Oral Valproic Acid in Patients with Retinitis Pigmentosa

“…The median logMAR BCVA improved from 1.8 1–3 in group 1 at baseline to 1.3 (0.6–1.3) at 1-year follow-up in group 1 (30 eyes). This change was statistically significant ( P <0.001).…”

Molecular Mechanisms of Rhodopsin Retinitis Pigmentosa and the Efficacy of Pharmacological Rescue

“…47 Finally, vitamin A palmitate slightly slows the progressive decay of electroretinogram (ERG) responses in RP patients. [48][49][50] These studies support the use of pharmacological rescue in rhodopsin RP. However, it is unknown whether this strategy and the protein-misfolding disease model on which it is based are relevant to only a few RP rhodopsins or are more widely applicable.…”

Vitamin A Intake and Hip Fractures Among Postmenopausal Women

“…However, multivitamins contain other essential nutrients and have been associated with lower risk of coronary disease, 38 colon cancer, 39 and breast cancer 40 in this same cohort. Also, the findings from this study do not imply that supplementation with vitamin A should be discontinued when used for conditions such as retinitis pigmentosa, for which benefits have been documented, 41 although monitoring of bone health may be appropriate.…”

Efficacy of Oral Valproic Acid in Patients with Retinitis Pigmentosa

“…The median logMAR BCVA improved from 1.8 1–3 in group 1 at baseline to 1.3 (0.6–1.3) at 1-year follow-up in group 1 (30 eyes). This change was statistically significant ( P <0.001).…”