Visual Results after Surgical Removal of Subfoveal Choroidal Neovascular Membranes

Surgical excision of subfoveal neovascular membranes

“…The recurrence rates reported by Thomas et al 23 are similarly favourable. In the authors' experience excised CNV are almost always found at surgery to be larger than predicted pre-operatively by clinical or angiographic appearance.…”

Potential long-term inhibition of ocular neovascularisation by recombinant adeno-associated virus-mediated secretion gene therapy

“…31 However, all these approaches do not address the underlying stimuli of NV and recurrences are a significant problem. [32][33][34] Therefore, new therapies aimed at blocking the underlying stimuli for new vessel growth are necessary to achieve better treatment for these patients. Treatment with sFlt-1, a naturally-occurring truncated and secreted form of VEGF receptor Flt-1, has been shown to inhibit angiogenesis in a variety of disease models.…”

Transplante autólogo do epitélio pigmentado da retina na degeneração macular relacionada com a idade

“…Com o desenvolvimento de técnicas cirúrgicas para remover membranas sub-retinianas em olhos com síndrome da presumida histoplasmose ocular e DMRI neovascular, uma intervenção cirúrgica mais controlada para transplante sub-retiniano de células em suspensão e lâmi-na de tecido tornaram-se mais viáveis. Além disso, instrumentos mais finos e com maior precisão foram desenvolvidos reduzindo o trauma mecânico (9)(10)(11) . O transplante do EPR pareceu, portanto ser um caminho lógico para restaurar a visão em pacientes com DMRI.…”