Violaceous rash of dorsal fingers in a woman. Diagnosis: chilblain lupus erythematosus (perniosis)

Fisher, David A.; Everett, Mark Allen

doi:10.1001/archderm.132.4.459

Cited by 6 publications

(2 citation statements)

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“…These patients may have positive ANA or arthralgia but do not usually progress to SLE. Sporadic CHLE typically presents in middle-aged females rather than children and may be accompanied by discoid lupus [ 79 , 82 , 83 ], Raynaud's phenomenon, and livedo reticularis [ 79 , 84 ]. In spontaneous CHLE, progression to SLE has been documented in as high as 18% of cases [ 79 ].…”

Section: Cutaneous Manifestations Of Lupusmentioning

confidence: 99%

“…Many cases of CHLE are unresponsive to antimalarials [ 23 ]. Successful treatment with mycophenolate mofetil has been reported in refractory spontaneous cases [ 83 , 84 ]. Baricitinib alleviated symptoms in 3 patients with familial CHLE [ 81 , 85 ], and use of ruxolitinib has successfully treated two cases of CHLE [ 86 , 87 ].…”

Section: Cutaneous Manifestations Of Lupusmentioning

confidence: 99%

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Cutaneous Manifestations of “Lupus”: Systemic Lupus Erythematosus and Beyond

Cooper

Pisano

Shapiro

2021

International Journal of Rheumatology

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Lupus, Latin for “wolf,” is a term used to describe many dermatologic conditions, some of which are related to underlying systemic lupus erythematosus, while others are distinct disease processes. Cutaneous lupus erythematosus includes a wide array of visible skin manifestations and can progress to systemic lupus erythematosus in some cases. Cutaneous lupus can be subdivided into three main categories: acute cutaneous lupus erythematosus, subacute cutaneous lupus erythematosus, and chronic cutaneous lupus erythematosus. Physical exam, laboratory studies, and histopathology enable differentiation of cutaneous lupus subtypes. This differentiation is paramount as the subtype of cutaneous lupus informs upon treatment, disease monitoring, and prognostication. This review outlines the different cutaneous manifestations of lupus erythematosus and provides an update on both topical and systemic treatment options for these patients. Other conditions that utilize the term “lupus” but are not cutaneous lupus erythematosus are also discussed.

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