Viability Assays of PLLA Fibrous Membranes Produced by Rotary Jet Spinning for Application in Tissue Engineering

Abstract

Tissue engineering suggests different forms to reconstruct tissues and organs. One of the ways is through the use of polymeric biomaterials such as poly(L-lactic acid) (PLLA). PLLA is a recognized material in tissue engineering due to its characteristics as biocompatibility and bioresorbability. In this work PLLA fibrous membranes were produced HIGHLIGHTS • PLLA fibrous membranes were produced by rotary jet spinning. • Membranes were subjected to preliminary in vitro assays to verify cytotoxicity. • Direct cytotoxicity assays performed with fibroblastic and osteoblastic cells. • PLLA membranes produced by rotary jet spinning showed promising results. Ciocca, B.E.; et al.